Pre-diagnostic alcohol consumption and breast cancer recurrence and mortality: results from a prospective cohort with a wide range of variation in alcohol intake

Marianne Holm, Anja Olsen, Jane Hvarregaard Christensen, Niels T Kroman, Pernille Envold Hansen Bidstrup, Christoffer Johansen, Kim Overvad, Anne Tjønneland

34 Citationer (Scopus)

Abstract

The association between pre-diagnostic alcohol consumption and breast cancer recurrence and breast cancer specific mortality was investigated in 1,052 women diagnosed with early breast cancer in a prospective cohort of 29,875 women. Known clinical, lifestyle and socioeconomic risk factors were evaluated and adjusted for in multivariate analysis. We found a modest but significant association between pre-diagnostic alcohol consumption and breast cancer recurrence with a median follow-up of six years after date of diagnosis, both when using baseline measures of alcohol intake (HR, 1.65; 95% CI, 1.02-2.67; >2 units/day vs. ≤1 unit/day) and cumulated alcohol intake (HR, 2.02; 95% CI, 1.06-3.85; >40 drinking years vs. 0
OriginalsprogEngelsk
TidsskriftInternational journal of cancer. Journal international du cancer
Vol/bind132
Udgave nummer3
Sider (fra-til)686-94
Antal sider9
DOI
StatusUdgivet - 2013

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