TY - JOUR
T1 - Pre-asthma
T2 - a useful concept for prevention and disease-modification? A EUFOREA paper. Part 1-allergic asthma
AU - Scadding, G
AU - McDonald, M
AU - Backer, V
AU - Scadding, G
AU - Bernal-Sprekelsen, M
AU - Conti, D M
AU - De Corso, E
AU - Diamant, Z
AU - Gray, C
AU - Hopkins, C
AU - Jesenak, M
AU - Johansen, P
AU - Kappen, J
AU - Mullol, J
AU - Price, D
AU - Quirce, S
AU - Reitsma, S
AU - Salmi, S
AU - Senior, B
AU - Thyssen, J P
AU - Wahn, U
AU - Hellings, P W
N1 - © 2024 Scadding, McDonald, Backer, Scadding, Bernal-Sprekelsen, Conti, De Corso, Diamant, Gray, Hopkins, Jesenak, Johansen, Kappen, Mullol, Price, Quirce, Reitsma, Salmi, Senior, Thyssen, Wahn and Hellings.
PY - 2023
Y1 - 2023
N2 - Asthma, which affects some 300 million people worldwide and caused 455,000 deaths in 2019, is a significant burden to suffers and to society. It is the most common chronic disease in children and represents one of the major causes for years lived with disability. Significant efforts are made by organizations such as WHO in improving the diagnosis, treatment and monitoring of asthma. However asthma prevention has been less studied. Currently there is a concept of pre- diabetes which allows a reduction in full blown diabetes if diet and exercise are undertaken. Similar predictive states are found in Alzheimer's and Parkinson's diseases. In this paper we explore the possibilities for asthma prevention, both at population level and also investigate the possibility of defining a state of pre-asthma, in which intensive treatment could reduce progression to asthma. Since asthma is a heterogeneous condition, this paper is concerned with allergic asthma. A subsequent one will deal with late onset eosinophilic asthma.
AB - Asthma, which affects some 300 million people worldwide and caused 455,000 deaths in 2019, is a significant burden to suffers and to society. It is the most common chronic disease in children and represents one of the major causes for years lived with disability. Significant efforts are made by organizations such as WHO in improving the diagnosis, treatment and monitoring of asthma. However asthma prevention has been less studied. Currently there is a concept of pre- diabetes which allows a reduction in full blown diabetes if diet and exercise are undertaken. Similar predictive states are found in Alzheimer's and Parkinson's diseases. In this paper we explore the possibilities for asthma prevention, both at population level and also investigate the possibility of defining a state of pre-asthma, in which intensive treatment could reduce progression to asthma. Since asthma is a heterogeneous condition, this paper is concerned with allergic asthma. A subsequent one will deal with late onset eosinophilic asthma.
UR - http://www.scopus.com/inward/record.url?scp=85184725138&partnerID=8YFLogxK
U2 - 10.3389/falgy.2023.1291185
DO - 10.3389/falgy.2023.1291185
M3 - Review
C2 - 38352244
SN - 2673-6101
VL - 4
JO - Frontiers in allergy
JF - Frontiers in allergy
M1 - 1291185
ER -