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Post-error adjustment among children aged 7 years with a familial high risk of schizophrenia or bipolar disorder: A population-based cohort study

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@article{6cc0a13f0fc448c4bbce6d9b5e8efd94,
title = "Post-error adjustment among children aged 7 years with a familial high risk of schizophrenia or bipolar disorder: A population-based cohort study",
abstract = "The cognitive control system matures gradually with age and shows age-related sex differences. To gain knowledge concerning error adaptation in familial high-risk groups, investigating error adaptation among the offspring of parents with severe mental disorders is important and may contribute to the understanding of cognitive functioning in at-risk individuals. We identified an observational cohort through Danish registries and measured error adaptation using an Eriksen flanker paradigm. We tested 497 7-year-old children with a familial high risk of schizophrenia (N = 192) or bipolar disorder (N = 116) for deficits in error adaptation compared with a control group (N = 189). We investigated whether error adaptation differed between high-risk groups compared with controls and sex differences in the adaptation to errors, irrespective of high-risk status. Overall, children exhibited post-error slowing (PES), but the slowing of responses did not translate to significant improvements in accuracy. No differences were detected between either high-risk group compared with the controls. Boys showed less PES and PES after incongruent trials than girls. Our results suggest that familial high risk of severe mental disorders does not influence error adaptation at this early stage of cognitive control development. Error adaptation behavior at age 7 years shows specific sex differences.",
keywords = "bipolar disorder, error adaptation, post-error improvement of accuracy, post-error slowing, schizophrenia",
author = "Burton, {Birgitte Klee} and Anders Petersen and Heike Eichele and Nicoline Hemager and Spang, {Katrine S} and Ditte Ellersgaard and Christiani, {Camilla Jerlang} and Aja Greve and Ditte Gantriis and Jepsen, {Jens Richardt M} and Ole Mors and Merete Nordentoft and Thorup, {Anne AE} and Plessen, {Kerstin Jessica} and Signe Vangkilde",
year = "2021",
month = may,
day = "17",
doi = "10.1017/S0954579421000444",
language = "English",
pages = "1--11",
journal = "Development and Psychopathology",
issn = "0954-5794",
publisher = "Cambridge University Press",

}

RIS

TY - JOUR

T1 - Post-error adjustment among children aged 7 years with a familial high risk of schizophrenia or bipolar disorder

T2 - A population-based cohort study

AU - Burton, Birgitte Klee

AU - Petersen, Anders

AU - Eichele, Heike

AU - Hemager, Nicoline

AU - Spang, Katrine S

AU - Ellersgaard, Ditte

AU - Christiani, Camilla Jerlang

AU - Greve, Aja

AU - Gantriis, Ditte

AU - Jepsen, Jens Richardt M

AU - Mors, Ole

AU - Nordentoft, Merete

AU - Thorup, Anne AE

AU - Plessen, Kerstin Jessica

AU - Vangkilde, Signe

PY - 2021/5/17

Y1 - 2021/5/17

N2 - The cognitive control system matures gradually with age and shows age-related sex differences. To gain knowledge concerning error adaptation in familial high-risk groups, investigating error adaptation among the offspring of parents with severe mental disorders is important and may contribute to the understanding of cognitive functioning in at-risk individuals. We identified an observational cohort through Danish registries and measured error adaptation using an Eriksen flanker paradigm. We tested 497 7-year-old children with a familial high risk of schizophrenia (N = 192) or bipolar disorder (N = 116) for deficits in error adaptation compared with a control group (N = 189). We investigated whether error adaptation differed between high-risk groups compared with controls and sex differences in the adaptation to errors, irrespective of high-risk status. Overall, children exhibited post-error slowing (PES), but the slowing of responses did not translate to significant improvements in accuracy. No differences were detected between either high-risk group compared with the controls. Boys showed less PES and PES after incongruent trials than girls. Our results suggest that familial high risk of severe mental disorders does not influence error adaptation at this early stage of cognitive control development. Error adaptation behavior at age 7 years shows specific sex differences.

AB - The cognitive control system matures gradually with age and shows age-related sex differences. To gain knowledge concerning error adaptation in familial high-risk groups, investigating error adaptation among the offspring of parents with severe mental disorders is important and may contribute to the understanding of cognitive functioning in at-risk individuals. We identified an observational cohort through Danish registries and measured error adaptation using an Eriksen flanker paradigm. We tested 497 7-year-old children with a familial high risk of schizophrenia (N = 192) or bipolar disorder (N = 116) for deficits in error adaptation compared with a control group (N = 189). We investigated whether error adaptation differed between high-risk groups compared with controls and sex differences in the adaptation to errors, irrespective of high-risk status. Overall, children exhibited post-error slowing (PES), but the slowing of responses did not translate to significant improvements in accuracy. No differences were detected between either high-risk group compared with the controls. Boys showed less PES and PES after incongruent trials than girls. Our results suggest that familial high risk of severe mental disorders does not influence error adaptation at this early stage of cognitive control development. Error adaptation behavior at age 7 years shows specific sex differences.

KW - bipolar disorder

KW - error adaptation

KW - post-error improvement of accuracy

KW - post-error slowing

KW - schizophrenia

UR - http://www.scopus.com/inward/record.url?scp=85106034353&partnerID=8YFLogxK

U2 - 10.1017/S0954579421000444

DO - 10.1017/S0954579421000444

M3 - Journal article

C2 - 33993894

SP - 1

EP - 11

JO - Development and Psychopathology

JF - Development and Psychopathology

SN - 0954-5794

ER -

ID: 65894807