Pooled human platelet lysate versus fetal bovine serum-investigating the proliferation rate, chromosome stability and angiogenic potential of human adipose tissue-derived stem cells intended for clinical use

Stig-Frederik Trojahn Kølle; Roberto S Oliveri; Peter V Glovinski; Eva Maria Kirchhoff; Anders Bruun Mathiasen; Jens Jørgen Elberg; Peter Stemann Andersen; Krzysztof Tadeusz Drzewiecki; Anne Fischer-Nielsen

doi:10.1016/j.jcyt.2013.01.217

Pooled human platelet lysate versus fetal bovine serum-investigating the proliferation rate, chromosome stability and angiogenic potential of human adipose tissue-derived stem cells intended for clinical use

Stig-Frederik Trojahn Kølle, Roberto S Oliveri, Peter V Glovinski, Eva Maria Kirchhoff, Anders Bruun Mathiasen, Jens Jørgen Elberg, Peter Stemann Andersen, Krzysztof Tadeusz Drzewiecki, Anne Fischer-Nielsen

84 Citationer (Scopus)

Abstract

Because of an increasing focus on the use of adipose-derived stem cells (ASCs) in clinical trials, the culture conditions for these cells are being optimized. We compared the proliferation rates and chromosomal stability of ASCs that had been cultured in Dulbecco's modified Eagle's Medium (DMEM) supplemented with either pooled human platelet lysate (pHPL) or clinical-grade fetal bovine serum (FBS) (DMEM(pHPL) versus DMEM(FBS)).

Originalsprog	Engelsk
Tidsskrift	Cytotherapy
Vol/bind	15
Udgave nummer	9
Sider (fra-til)	1086-97
Antal sider	12
ISSN	1465-3249
DOI	https://doi.org/10.1016/j.jcyt.2013.01.217
Status	Udgivet - sep. 2013

Adgang til dokumentet

10.1016/j.jcyt.2013.01.217

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Citationsformater

Trojahn Kølle, S.-F., Oliveri, R. S., Glovinski, P. V., Kirchhoff, E. M., Mathiasen, A. B., Elberg, J. J., Andersen, P. S., Drzewiecki, K. T., & Fischer-Nielsen, A. (2013). Pooled human platelet lysate versus fetal bovine serum-investigating the proliferation rate, chromosome stability and angiogenic potential of human adipose tissue-derived stem cells intended for clinical use. Cytotherapy, 15(9), 1086-97. https://doi.org/10.1016/j.jcyt.2013.01.217

Pooled human platelet lysate versus fetal bovine serum-investigating the proliferation rate, chromosome stability and angiogenic potential of human adipose tissue-derived stem cells intended for clinical use. / Trojahn Kølle, Stig-Frederik; Oliveri, Roberto S; Glovinski, Peter V et al.
I: Cytotherapy, Bind 15, Nr. 9, 09.2013, s. 1086-97.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Trojahn Kølle, S-F, Oliveri, RS, Glovinski, PV , Kirchhoff, EM , Mathiasen, AB, Elberg, JJ, Andersen, PS, Drzewiecki, KT & Fischer-Nielsen, A 2013, 'Pooled human platelet lysate versus fetal bovine serum-investigating the proliferation rate, chromosome stability and angiogenic potential of human adipose tissue-derived stem cells intended for clinical use', Cytotherapy, bind 15, nr. 9, s. 1086-97. https://doi.org/10.1016/j.jcyt.2013.01.217

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title = "Pooled human platelet lysate versus fetal bovine serum-investigating the proliferation rate, chromosome stability and angiogenic potential of human adipose tissue-derived stem cells intended for clinical use",

abstract = "Because of an increasing focus on the use of adipose-derived stem cells (ASCs) in clinical trials, the culture conditions for these cells are being optimized. We compared the proliferation rates and chromosomal stability of ASCs that had been cultured in Dulbecco's modified Eagle's Medium (DMEM) supplemented with either pooled human platelet lysate (pHPL) or clinical-grade fetal bovine serum (FBS) (DMEM(pHPL) versus DMEM(FBS)).",

author = "{Trojahn K{\o}lle}, Stig-Frederik and Oliveri, {Roberto S} and Glovinski, {Peter V} and Kirchhoff, {Eva Maria} and Mathiasen, {Anders Bruun} and Elberg, {Jens J{\o}rgen} and Andersen, {Peter Stemann} and Drzewiecki, {Krzysztof Tadeusz} and Anne Fischer-Nielsen",

year = "2013",

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doi = "10.1016/j.jcyt.2013.01.217",

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AU - Trojahn Kølle, Stig-Frederik

AU - Oliveri, Roberto S

AU - Glovinski, Peter V

AU - Kirchhoff, Eva Maria

AU - Mathiasen, Anders Bruun

AU - Elberg, Jens Jørgen

AU - Andersen, Peter Stemann

AU - Drzewiecki, Krzysztof Tadeusz

AU - Fischer-Nielsen, Anne

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AB - Because of an increasing focus on the use of adipose-derived stem cells (ASCs) in clinical trials, the culture conditions for these cells are being optimized. We compared the proliferation rates and chromosomal stability of ASCs that had been cultured in Dulbecco's modified Eagle's Medium (DMEM) supplemented with either pooled human platelet lysate (pHPL) or clinical-grade fetal bovine serum (FBS) (DMEM(pHPL) versus DMEM(FBS)).

U2 - 10.1016/j.jcyt.2013.01.217

DO - 10.1016/j.jcyt.2013.01.217

M3 - Journal article

C2 - 23602579

SN - 1465-3249

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JO - Cytotherapy

JF - Cytotherapy

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