Pooled analysis of phase II trials evaluating weekly or conventional cisplatin as first-line therapy for advanced urothelial carcinoma

Benjamin L Maughan; Neeraj Agarwal; Syed A Hussain; Kenneth M Boucher; Hans Von Der Maase; Donald S Kaufman; Vito Lorusso; Malcolm J Moore; Matthew D Galsky; Guru Sonpavde

doi:10.1016/j.clgc.2012.12.007

Pooled analysis of phase II trials evaluating weekly or conventional cisplatin as first-line therapy for advanced urothelial carcinoma

Benjamin L Maughan, Neeraj Agarwal, Syed A Hussain, Kenneth M Boucher, Hans Von Der Maase, Donald S Kaufman, Vito Lorusso, Malcolm J Moore, Matthew D Galsky, Guru Sonpavde

6 Citationer (Scopus)

Abstract

Weekly gemcitabine with GC every 3-4 weeks is considered conventional first-line chemotherapy for advanced urothelial carcinoma (UC). Weekly split-dose cisplatin with wGC might be less toxic and have similar activity, but has not been compared with GC. We pooled published phase II trials of GC and wGC to compare efficacy and safety.

Originalsprog	Engelsk
Tidsskrift	Clinical Genitourinary Cancer (Online)
Vol/bind	11
Udgave nummer	3
Sider (fra-til)	316-20
Antal sider	5
ISSN	1938-0682
DOI	https://doi.org/10.1016/j.clgc.2012.12.007
Status	Udgivet - sep. 2013

Adgang til dokumentet

10.1016/j.clgc.2012.12.007

Citationsformater

Maughan, B. L., Agarwal, N., Hussain, S. A., Boucher, K. M., Von Der Maase, H., Kaufman, D. S., Lorusso, V., Moore, M. J., Galsky, M. D., & Sonpavde, G. (2013). Pooled analysis of phase II trials evaluating weekly or conventional cisplatin as first-line therapy for advanced urothelial carcinoma. Clinical Genitourinary Cancer (Online), 11(3), 316-20. https://doi.org/10.1016/j.clgc.2012.12.007

Maughan, BL, Agarwal, N, Hussain, SA, Boucher, KM, Von Der Maase, H, Kaufman, DS, Lorusso, V, Moore, MJ, Galsky, MD & Sonpavde, G 2013, 'Pooled analysis of phase II trials evaluating weekly or conventional cisplatin as first-line therapy for advanced urothelial carcinoma', Clinical Genitourinary Cancer (Online), bind 11, nr. 3, s. 316-20. https://doi.org/10.1016/j.clgc.2012.12.007

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abstract = "Weekly gemcitabine with GC every 3-4 weeks is considered conventional first-line chemotherapy for advanced urothelial carcinoma (UC). Weekly split-dose cisplatin with wGC might be less toxic and have similar activity, but has not been compared with GC. We pooled published phase II trials of GC and wGC to compare efficacy and safety.",

author = "Maughan, {Benjamin L} and Neeraj Agarwal and Hussain, {Syed A} and Boucher, {Kenneth M} and {Von Der Maase}, Hans and Kaufman, {Donald S} and Vito Lorusso and Moore, {Malcolm J} and Galsky, {Matthew D} and Guru Sonpavde",

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AU - Maughan, Benjamin L

AU - Agarwal, Neeraj

AU - Hussain, Syed A

AU - Boucher, Kenneth M

AU - Von Der Maase, Hans

AU - Kaufman, Donald S

AU - Lorusso, Vito

AU - Moore, Malcolm J

AU - Galsky, Matthew D

AU - Sonpavde, Guru

PY - 2013/9

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N2 - Weekly gemcitabine with GC every 3-4 weeks is considered conventional first-line chemotherapy for advanced urothelial carcinoma (UC). Weekly split-dose cisplatin with wGC might be less toxic and have similar activity, but has not been compared with GC. We pooled published phase II trials of GC and wGC to compare efficacy and safety.

AB - Weekly gemcitabine with GC every 3-4 weeks is considered conventional first-line chemotherapy for advanced urothelial carcinoma (UC). Weekly split-dose cisplatin with wGC might be less toxic and have similar activity, but has not been compared with GC. We pooled published phase II trials of GC and wGC to compare efficacy and safety.

U2 - 10.1016/j.clgc.2012.12.007

DO - 10.1016/j.clgc.2012.12.007

M3 - Journal article

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SN - 1938-0682

VL - 11

SP - 316

EP - 320

JO - Clinical Genitourinary Cancer (Online)

JF - Clinical Genitourinary Cancer (Online)

IS - 3

ER -

Pooled analysis of phase II trials evaluating weekly or conventional cisplatin as first-line therapy for advanced urothelial carcinoma

Abstract

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