Platformsforsøg

Anders Perner; Maj-Brit N Kjær; Hans-Christian Thorsen-Meyer; Benjamin S Kaas-Hansen; Marie W Munch; Marie O Collet; Camilla Rl Bruun; Aksel K. G.  Jensen; Theis Lange; Trine Albertsen; Claus Duedal Pedersen; Lone M Poulsen; Ole Mathiesen; Anne C Brøchner; Thomas Strøm; Lars W Andersen; Steffen Christensen; Bodil S Rasmussen; Olav L Schjørring; Mathias Maagaard; Morten Hylander Møller; Anders Granholm

Platformsforsøg

Anders Perner^*, Maj-Brit N Kjær, Hans-Christian Thorsen-Meyer, Benjamin S Kaas-Hansen, Marie W Munch, Marie O Collet, Camilla Rl Bruun, Aksel K. G. Jensen, Theis Lange, Trine Albertsen, Claus Duedal Pedersen, Lone M Poulsen, Ole Mathiesen, Anne C Brøchner, Thomas Strøm, Lars W Andersen, Steffen Christensen, Bodil S Rasmussen, Olav L Schjørring, Mathias MaagaardMorten Hylander Møller, Anders Granholm

^*Corresponding author af dette arbejde

Afdeling for Intensiv Behandling i Center for Kræft og Organsygdomme

Abstract

Platform trials focus on the perpetual testing of many interventions in a disease or a setting. These trials have lasting organizational, administrative, data, analytic, and operational frameworks making them highly efficient. The use of adaptation often increases the probabilities of allocating participants to better interventions and obtaining conclusive results. The COVID-19 pandemic showed the potential of platform trials as a fast and valid way to improved treatments. This review gives an overview of key concepts and elements using the Intensive Care Platform Trial (INCEPT) as an example.

Bidragets oversatte titel	Platform trials
Originalsprog	Dansk
Artikelnummer	V04230237
Tidsskrift	Ugeskrift for Laeger
Vol/bind	185
Udgave nummer	41
ISSN	0041-5782
Status	Udgivet - 9 okt. 2023

Emneord

COVID-19/epidemiology
Humans
Pandemics

Andre filer og links

https://ugeskriftet.dk/videnskab/platformsforsog

Citationsformater

Perner, A., Kjær, M.-B. N., Thorsen-Meyer, H.-C., Kaas-Hansen, B. S., Munch, M. W., Collet, M. O., Bruun, C. R., Jensen, A. K. G., Lange, T., Albertsen, T., Pedersen, C. D., Poulsen, L. M., Mathiesen, O., Brøchner, A. C., Strøm, T., Andersen, L. W., Christensen, S., Rasmussen, B. S., Schjørring, O. L., ... Granholm, A. (2023). Platformsforsøg. Ugeskrift for Laeger, 185(41), Artikel V04230237.

Perner, A , Kjær, M-BN , Thorsen-Meyer, H-C , Kaas-Hansen, BS , Munch, MW , Collet, MO , Bruun, CR, Jensen, AKG, Lange, T, Albertsen, T, Pedersen, CD, Poulsen, LM, Mathiesen, O, Brøchner, AC, Strøm, T, Andersen, LW, Christensen, S, Rasmussen, BS, Schjørring, OL, Maagaard, M, Møller, MH & Granholm, A 2023, 'Platformsforsøg', Ugeskrift for Laeger, bind 185, nr. 41, V04230237.

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abstract = "Platform trials focus on the perpetual testing of many interventions in a disease or a setting. These trials have lasting organizational, administrative, data, analytic, and operational frameworks making them highly efficient. The use of adaptation often increases the probabilities of allocating participants to better interventions and obtaining conclusive results. The COVID-19 pandemic showed the potential of platform trials as a fast and valid way to improved treatments. This review gives an overview of key concepts and elements using the Intensive Care Platform Trial (INCEPT) as an example.",

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T1 - Platformsforsøg

AU - Perner, Anders

AU - Kjær, Maj-Brit N

AU - Thorsen-Meyer, Hans-Christian

AU - Kaas-Hansen, Benjamin S

AU - Munch, Marie W

AU - Collet, Marie O

AU - Bruun, Camilla Rl

AU - Jensen, Aksel K. G.

AU - Lange, Theis

AU - Albertsen, Trine

AU - Pedersen, Claus Duedal

AU - Poulsen, Lone M

AU - Mathiesen, Ole

AU - Brøchner, Anne C

AU - Strøm, Thomas

AU - Andersen, Lars W

AU - Christensen, Steffen

AU - Rasmussen, Bodil S

AU - Schjørring, Olav L

AU - Maagaard, Mathias

AU - Møller, Morten Hylander

AU - Granholm, Anders

N1 - Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2023/10/9

Y1 - 2023/10/9

N2 - Platform trials focus on the perpetual testing of many interventions in a disease or a setting. These trials have lasting organizational, administrative, data, analytic, and operational frameworks making them highly efficient. The use of adaptation often increases the probabilities of allocating participants to better interventions and obtaining conclusive results. The COVID-19 pandemic showed the potential of platform trials as a fast and valid way to improved treatments. This review gives an overview of key concepts and elements using the Intensive Care Platform Trial (INCEPT) as an example.

AB - Platform trials focus on the perpetual testing of many interventions in a disease or a setting. These trials have lasting organizational, administrative, data, analytic, and operational frameworks making them highly efficient. The use of adaptation often increases the probabilities of allocating participants to better interventions and obtaining conclusive results. The COVID-19 pandemic showed the potential of platform trials as a fast and valid way to improved treatments. This review gives an overview of key concepts and elements using the Intensive Care Platform Trial (INCEPT) as an example.

KW - COVID-19/epidemiology

KW - Humans

KW - Pandemics

UR - https://ugeskriftet.dk/videnskab/platformsforsog

M3 - Review

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SN - 0041-5782

VL - 185

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

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M1 - V04230237

ER -

Platformsforsøg

Abstract

Emneord

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