@article{29ee934b8ba54f9498abe33e1bdd5560,
title = "Plasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming",
abstract = "Duct cells isolated from adult human pancreas can be reprogrammed to express islet beta cell genes by adenoviral transduction of the developmental transcription factor neurogenin3 (Ngn3). In this study we aimed to fully characterize the extent of this reprogramming and intended to improve it.",
keywords = "Adult, Animals, Basic Helix-Loop-Helix Transcription Factors, Binding Sites, Cell Transdifferentiation, Cells, Cultured, DNA-Binding Proteins, Gene Expression Profiling, Homeodomain Proteins, Humans, Insulin-Secreting Cells, Intracellular Signaling Peptides and Proteins, Maf Transcription Factors, Large, Membrane Proteins, Mice, Nerve Tissue Proteins, Pancreatic Ducts, Promoter Regions, Genetic, RNA, Messenger, Receptors, Notch, Recombinant Proteins, Signal Transduction, Trans-Activators, Transcription Factors, Transduction, Genetic",
author = "Nathalie Swales and Martens, {Geert A} and Stefan Bonn{\'e} and Yves Heremans and Rehannah Borup and {Van de Casteele}, Mark and Zhidong Ling and Daniel Pipeleers and Philippe Ravassard and Finn Nielsen and Jorge Ferrer and Harry Heimberg",
year = "2012",
doi = "10.1371/journal.pone.0037055",
language = "English",
volume = "7",
pages = "e37055",
journal = "P L o S One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "5",
}