TY - JOUR
T1 - Plasma pH does not influence the cerebral metabolic ratio during maximal whole body exercise
AU - Volianitis, Stefanos
AU - Rasmussen, Peter
AU - Seifert, Thomas
AU - Nielsen, H B
AU - Secher, N H
PY - 2011/1/15
Y1 - 2011/1/15
N2 - Exercise lowers the cerebral metabolic ratio of O2 to carbohydrate (glucose+1/2 lactate) and metabolic acidosis appears to promote cerebral lactate uptake. However, the influence of pH on cerebral lactate uptake and, in turn, on the cerebral metabolic ratio during exercise is not known. Sodium bicarbonate (Bicarb, 1 M; 350-500 ml) or an equal volume of normal saline (Sal) was infused intravenously at a constant rate during a '2000 m' maximal ergometer row in six male oarsmen (23±2 years; mean±S.D.). During the Sal trial, pH decreased from 7.41±0.01 at rest to 7.02±0.02 but only to 7.36±0.02 (P
AB - Exercise lowers the cerebral metabolic ratio of O2 to carbohydrate (glucose+1/2 lactate) and metabolic acidosis appears to promote cerebral lactate uptake. However, the influence of pH on cerebral lactate uptake and, in turn, on the cerebral metabolic ratio during exercise is not known. Sodium bicarbonate (Bicarb, 1 M; 350-500 ml) or an equal volume of normal saline (Sal) was infused intravenously at a constant rate during a '2000 m' maximal ergometer row in six male oarsmen (23±2 years; mean±S.D.). During the Sal trial, pH decreased from 7.41±0.01 at rest to 7.02±0.02 but only to 7.36±0.02 (P
U2 - 10.1113/jphysiol.2010.195636
DO - 10.1113/jphysiol.2010.195636
M3 - Journal article
C2 - 21098003
SN - 0022-3751
VL - 589
SP - 423
EP - 429
JO - Journal of Physiology
JF - Journal of Physiology
IS - Pt 2
ER -