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Region Hovedstaden - en del af Københavns Universitetshospital
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Plasma exchange in the intensive care unit: a narrative review

Publikation: Bidrag til tidsskriftReviewForskningpeer review

DOI

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  • Philippe R Bauer
  • Marlies Ostermann
  • Lene Russell
  • Chiara Robba
  • Sascha David
  • Bruno L Ferreyro
  • Joan Cid
  • Pedro Castro
  • Nicole P Juffermans
  • Luca Montini
  • Tasneem Pirani
  • Andry Van De Louw
  • Nathan Nielsen
  • Julia Wendon
  • Anne C Brignier
  • Miet Schetz
  • Jan T Kielstein
  • Jeffrey L Winters
  • Elie Azoulay
  • Nine-i investigators
Vis graf over relationer

In this narrative review, we discuss the relevant issues of therapeutic plasma exchange (TPE) in critically ill patients. For many conditions, the optimal indication, device type, frequency, duration, type of replacement fluid and criteria for stopping TPE are uncertain. TPE is a potentially lifesaving but also invasive procedure with risk of adverse events and complications and requires close monitoring by experienced teams. In the intensive care unit (ICU), the indications for TPE can be divided into (1) absolute, well-established, and evidence-based, for which TPE is recognized as first-line therapy, (2) relative, for which TPE is a recognized second-line treatment (alone or combined) and (3) rescue therapy, where TPE is used with a limited or theoretical evidence base. New indications are emerging and ongoing knowledge gaps, notably regarding the use of TPE during critical illness, support the establishment of a TPE registry dedicated to intensive care medicine.

OriginalsprogEngelsk
TidsskriftIntensive Care Medicine
Vol/bind48
Udgave nummer10
Sider (fra-til)1382-1396
Antal sider15
ISSN0342-4642
DOI
StatusUdgivet - okt. 2022

Bibliografisk note

© 2022. Springer-Verlag GmbH Germany, part of Springer Nature.

ID: 80403053