Placebo-controlled trial of amantadine for severe traumatic brain injury

Joseph T Giacino; John Whyte; Emilia Bagiella; Kathleen Kalmar; Nancy Childs; Allen Khademi; Bernd Eifert; David Long; Douglas I Katz; Sooja Cho; Stuart A Yablon; Marianne Luther; Flora M Hammond; Annette Nordenbo; Paul Novak; Walt Mercer; Petra Maurer-Karattup; Mark Sherer

doi:10.1056/NEJMoa1102609

Placebo-controlled trial of amantadine for severe traumatic brain injury

Joseph T Giacino, John Whyte, Emilia Bagiella, Kathleen Kalmar, Nancy Childs, Allen Khademi, Bernd Eifert, David Long, Douglas I Katz, Sooja Cho, Stuart A Yablon, Marianne Luther, Flora M Hammond, Annette Nordenbo, Paul Novak, Walt Mercer, Petra Maurer-Karattup, Mark Sherer

563 Citationer (Scopus)

Abstract

Amantadine hydrochloride is one of the most commonly prescribed medications for patients with prolonged disorders of consciousness after traumatic brain injury. Preliminary studies have suggested that amantadine may promote functional recovery.

Originalsprog	Engelsk
Tidsskrift	New England Journal of Medicine
Vol/bind	366
Udgave nummer	9
Sider (fra-til)	819-26
Antal sider	8
ISSN	0028-4793
DOI	https://doi.org/10.1056/NEJMoa1102609
Status	Udgivet - 2012

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10.1056/NEJMoa1102609

Citationsformater

Giacino, J. T., Whyte, J., Bagiella, E., Kalmar, K., Childs, N., Khademi, A., Eifert, B., Long, D., Katz, D. I., Cho, S., Yablon, S. A., Luther, M., Hammond, F. M., Nordenbo, A., Novak, P., Mercer, W., Maurer-Karattup, P., & Sherer, M. (2012). Placebo-controlled trial of amantadine for severe traumatic brain injury. New England Journal of Medicine, 366(9), 819-26. https://doi.org/10.1056/NEJMoa1102609

Giacino, JT, Whyte, J, Bagiella, E, Kalmar, K, Childs, N, Khademi, A, Eifert, B, Long, D, Katz, DI, Cho, S, Yablon, SA, Luther, M, Hammond, FM, Nordenbo, A, Novak, P, Mercer, W, Maurer-Karattup, P & Sherer, M 2012, 'Placebo-controlled trial of amantadine for severe traumatic brain injury', New England Journal of Medicine, bind 366, nr. 9, s. 819-26. https://doi.org/10.1056/NEJMoa1102609

@article{3e72382ffbaf47f2aefd6ee39139f240,

title = "Placebo-controlled trial of amantadine for severe traumatic brain injury",

abstract = "Amantadine hydrochloride is one of the most commonly prescribed medications for patients with prolonged disorders of consciousness after traumatic brain injury. Preliminary studies have suggested that amantadine may promote functional recovery.",

keywords = "Adult, Amantadine, Brain Injuries, Coma, Post-Head Injury, Disability Evaluation, Dopamine Agents, Female, Glasgow Coma Scale, Humans, Male, Persistent Vegetative State, Recovery of Function",

author = "Giacino, {Joseph T} and John Whyte and Emilia Bagiella and Kathleen Kalmar and Nancy Childs and Allen Khademi and Bernd Eifert and David Long and Katz, {Douglas I} and Sooja Cho and Yablon, {Stuart A} and Marianne Luther and Hammond, {Flora M} and Annette Nordenbo and Paul Novak and Walt Mercer and Petra Maurer-Karattup and Mark Sherer",

year = "2012",

doi = "10.1056/NEJMoa1102609",

language = "English",

volume = "366",

pages = "819--26",

journal = "New England Journal of Medicine",

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TY - JOUR

T1 - Placebo-controlled trial of amantadine for severe traumatic brain injury

AU - Giacino, Joseph T

AU - Whyte, John

AU - Bagiella, Emilia

AU - Kalmar, Kathleen

AU - Childs, Nancy

AU - Khademi, Allen

AU - Eifert, Bernd

AU - Long, David

AU - Katz, Douglas I

AU - Cho, Sooja

AU - Yablon, Stuart A

AU - Luther, Marianne

AU - Hammond, Flora M

AU - Nordenbo, Annette

AU - Novak, Paul

AU - Mercer, Walt

AU - Maurer-Karattup, Petra

AU - Sherer, Mark

PY - 2012

Y1 - 2012

N2 - Amantadine hydrochloride is one of the most commonly prescribed medications for patients with prolonged disorders of consciousness after traumatic brain injury. Preliminary studies have suggested that amantadine may promote functional recovery.

AB - Amantadine hydrochloride is one of the most commonly prescribed medications for patients with prolonged disorders of consciousness after traumatic brain injury. Preliminary studies have suggested that amantadine may promote functional recovery.

KW - Adult

KW - Amantadine

KW - Brain Injuries

KW - Coma, Post-Head Injury

KW - Disability Evaluation

KW - Dopamine Agents

KW - Female

KW - Glasgow Coma Scale

KW - Humans

KW - Male

KW - Persistent Vegetative State

KW - Recovery of Function

U2 - 10.1056/NEJMoa1102609

DO - 10.1056/NEJMoa1102609

M3 - Journal article

C2 - 22375973

VL - 366

SP - 819

EP - 826

JO - New England Journal of Medicine

JF - New England Journal of Medicine

SN - 0028-4793

IS - 9

ER -

Placebo-controlled trial of amantadine for severe traumatic brain injury

Abstract

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