Pituitary gastrins occur in corticotrophs and melanotrophs

L I Larsson, J F Rehfeld

Abstract

The gut hormone gastrin was identified in pituitary cells containing adrenocorticotropic hormone and alpha-melanocyte--stimulating hormone by region-specific immunocytochemistry and radioimmunoassay. Smaller amounts of gastrin were found in nerve fibers of the neural lobe and pituitary stalk. Since adrenocorticotropic hormone--like peptides occur in antropyloric gastrin cells, these data indicate a considerable similarity in peptide composition of pituitary and gastrointestinal endocrine cells and reinforces questions of multiple hormone production.

OriginalsprogEngelsk
TidsskriftScience
Vol/bind213
Udgave nummer4509
Sider (fra-til)768-70
Antal sider3
ISSN0036-8075
DOI
StatusUdgivet - 14 aug. 1981
Udgivet eksterntJa

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