Pitfalls in diagnostic gastrin measurements

Jens F Rehfeld; Linda Bardram; Linda Hilsted; Pierre Poitras; Jens P Goetze

doi:10.1373/clinchem.2011.179929

Pitfalls in diagnostic gastrin measurements

Jens F Rehfeld, Linda Bardram, Linda Hilsted, Pierre Poitras, Jens P Goetze

Afdeling for Klinisk Biokemi DIA

38 Citationer (Scopus)

Abstract

Gastrin measurements are performed primarily for the diagnosis of gastrin-producing tumors, gastrinomas, which cause the Zollinger-Ellison syndrome (ZES). Gastrin circulates as several bioactive peptides, however, and the peptide pattern in gastrinoma patients often deviates from normal. Therefore, it is necessary to measure all forms of gastrin.

Originalsprog	Engelsk
Tidsskrift	Clinical Chemistry (Washington, DC)
Vol/bind	58
Udgave nummer	5
Sider (fra-til)	831-6
Antal sider	6
ISSN	0009-9147
DOI	https://doi.org/10.1373/clinchem.2011.179929
Status	Udgivet - 2012

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10.1373/clinchem.2011.179929

Citationsformater

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title = "Pitfalls in diagnostic gastrin measurements",

abstract = "Gastrin measurements are performed primarily for the diagnosis of gastrin-producing tumors, gastrinomas, which cause the Zollinger-Ellison syndrome (ZES). Gastrin circulates as several bioactive peptides, however, and the peptide pattern in gastrinoma patients often deviates from normal. Therefore, it is necessary to measure all forms of gastrin.",

keywords = "Amino Acid Sequence, Antibody Specificity, Gastrinoma, Gastrins, Humans, Immunoassay, Molecular Sequence Data, Reagent Kits, Diagnostic, Sensitivity and Specificity, Tumor Markers, Biological, Zollinger-Ellison Syndrome",

author = "Rehfeld, {Jens F} and Linda Bardram and Linda Hilsted and Pierre Poitras and Goetze, {Jens P}",

year = "2012",

doi = "10.1373/clinchem.2011.179929",

language = "English",

volume = "58",

pages = "831--6",

journal = "Clinical Chemistry (Washington, DC)",

issn = "0009-9147",

publisher = "Oxford University Press",

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TY - JOUR

T1 - Pitfalls in diagnostic gastrin measurements

AU - Rehfeld, Jens F

AU - Bardram, Linda

AU - Hilsted, Linda

AU - Poitras, Pierre

AU - Goetze, Jens P

PY - 2012

Y1 - 2012

N2 - Gastrin measurements are performed primarily for the diagnosis of gastrin-producing tumors, gastrinomas, which cause the Zollinger-Ellison syndrome (ZES). Gastrin circulates as several bioactive peptides, however, and the peptide pattern in gastrinoma patients often deviates from normal. Therefore, it is necessary to measure all forms of gastrin.

AB - Gastrin measurements are performed primarily for the diagnosis of gastrin-producing tumors, gastrinomas, which cause the Zollinger-Ellison syndrome (ZES). Gastrin circulates as several bioactive peptides, however, and the peptide pattern in gastrinoma patients often deviates from normal. Therefore, it is necessary to measure all forms of gastrin.

KW - Amino Acid Sequence

KW - Antibody Specificity

KW - Gastrinoma

KW - Gastrins

KW - Humans

KW - Immunoassay

KW - Molecular Sequence Data

KW - Reagent Kits, Diagnostic

KW - Sensitivity and Specificity

KW - Tumor Markers, Biological

KW - Zollinger-Ellison Syndrome

U2 - 10.1373/clinchem.2011.179929

DO - 10.1373/clinchem.2011.179929

M3 - Review

C2 - 22419747

SN - 0009-9147

VL - 58

SP - 831

EP - 836

JO - Clinical Chemistry (Washington, DC)

JF - Clinical Chemistry (Washington, DC)

IS - 5

ER -

Pitfalls in diagnostic gastrin measurements

Abstract

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