Physical activity, sedentary behaviour, and childhood asthma: a European collaborative analysis

Marianne Eijkemans; Monique Mommers; Margreet W Harskamp-van Ginkel; Tanja G M Vrijkotte; Johnny Ludvigsson; Åshild Faresjö; Anna Bergström; Sandra Ekström; Veit Grote; Berthold Koletzko; Klaus Bønnelykke; Anders Ulrik Eliasen; Peter Bager; Mads Melbye; Isabella Annesi-Maesano; Nour Baïz; Henrique Barros; Ana Cristina Santos; Liesbeth Duijts; Sara M Mensink-Bout; Claudia Flexeder; Sibylle Koletzko; Tamara Schikowski; Merete Åse Eggesbø; Virissa Lenters; Guillermo Fernández-Tardón; Mikel Subiza-Perez; Judith Garcia-Aymerich; Mónica López-Vicente; Jordi Sunyer; Maties Torrent; Ferran Ballester; Cecily Kelleher; John Mehegan; Andrea von Berg; Gunda Herberth; Marie Standl; Claudia E Kuehni; Eva S L Pedersen; Maria Jansen; Ulrike Gehring; Jolanda M A Boer; Graham Devereux; Steve Turner; Ville Peltola; Hanna Lagström; Hazel M Inskip; Katharine C Pike; Geertje W Dalmeijer; Cornelis K van der Ent; Carel Thijs

doi:10.1136/bmjresp-2023-001630

Physical activity, sedentary behaviour, and childhood asthma: a European collaborative analysis

Marianne Eijkemans, Monique Mommers, Margreet W Harskamp-van Ginkel, Tanja G M Vrijkotte, Johnny Ludvigsson, Åshild Faresjö, Anna Bergström, Sandra Ekström, Veit Grote, Berthold Koletzko, Klaus Bønnelykke, Anders Ulrik Eliasen, Peter Bager, Mads Melbye, Isabella Annesi-Maesano, Nour Baïz, Henrique Barros, Ana Cristina Santos, Liesbeth Duijts, Sara M Mensink-BoutClaudia Flexeder, Sibylle Koletzko, Tamara Schikowski, Merete Åse Eggesbø, Virissa Lenters, Guillermo Fernández-Tardón, Mikel Subiza-Perez, Judith Garcia-Aymerich, Mónica López-Vicente, Jordi Sunyer, Maties Torrent, Ferran Ballester, Cecily Kelleher, John Mehegan, Andrea von Berg, Gunda Herberth, Marie Standl, Claudia E Kuehni, Eva S L Pedersen, Maria Jansen, Ulrike Gehring, Jolanda M A Boer, Graham Devereux, Steve Turner, Ville Peltola, Hanna Lagström, Hazel M Inskip, Katharine C Pike, Geertje W Dalmeijer, Cornelis K van der Ent, Carel Thijs

Copenhagen Prospective Studies on Asthma in Childhood

3 Citationer (Scopus)

Abstract

OBJECTIVES: To investigate the associations of physical activity (PA) and sedentary behaviour in early childhood with asthma and reduced lung function in later childhood within a large collaborative study.

DESIGN: Pooling of longitudinal data from collaborating birth cohorts using meta-analysis of separate cohort-specific estimates and analysis of individual participant data of all cohorts combined.

SETTING: Children aged 0-18 years from 26 European birth cohorts.

PARTICIPANTS: 136 071 individual children from 26 cohorts, with information on PA and/or sedentary behaviour in early childhood and asthma assessment in later childhood.

MAIN OUTCOME MEASURE: Questionnaire-based current asthma and lung function measured by spirometry (forced expiratory volume in 1 s (FEV1), FEV1/forced vital capacity) at age 6-18 years.

RESULTS: Questionnaire-based and accelerometry-based PA and sedentary behaviour at age 3-5 years was not associated with asthma at age 6-18 years (PA in hours/day adjusted OR 1.01, 95% CI 0.98 to 1.04; sedentary behaviour in hours/day adjusted OR 1.03, 95% CI 0.99 to 1.07). PA was not associated with lung function at any age. Analyses of sedentary behaviour and lung function showed inconsistent results.

CONCLUSIONS: Reduced PA and increased sedentary behaviour before 6 years of age were not associated with the presence of asthma later in childhood.

Originalsprog	Engelsk
Artikelnummer	e001630
Tidsskrift	BMJ Open Respiratory Research
Vol/bind	11
Udgave nummer	1
ISSN	2052-4439
DOI	https://doi.org/10.1136/bmjresp-2023-001630
Status	Udgivet - 15 aug. 2024

Adgang til dokumentet

10.1136/bmjresp-2023-001630Licens: CC BY-NC

Andre filer og links

Link to publication in Scopus

Citationsformater

Eijkemans, M., Mommers, M., Harskamp-van Ginkel, M. W., Vrijkotte, T. G. M., Ludvigsson, J., Faresjö, Å., Bergström, A., Ekström, S., Grote, V., Koletzko, B., Bønnelykke, K., Eliasen, A. U., Bager, P., Melbye, M., Annesi-Maesano, I., Baïz, N., Barros, H., Santos, A. C., Duijts, L., ... Thijs, C. (2024). Physical activity, sedentary behaviour, and childhood asthma: a European collaborative analysis. BMJ Open Respiratory Research, 11(1), Artikel e001630. https://doi.org/10.1136/bmjresp-2023-001630

Eijkemans, M, Mommers, M, Harskamp-van Ginkel, MW, Vrijkotte, TGM, Ludvigsson, J, Faresjö, Å, Bergström, A, Ekström, S, Grote, V, Koletzko, B, Bønnelykke, K , Eliasen, AU, Bager, P, Melbye, M, Annesi-Maesano, I, Baïz, N, Barros, H, Santos, AC, Duijts, L, Mensink-Bout, SM, Flexeder, C, Koletzko, S, Schikowski, T, Eggesbø, MÅ, Lenters, V, Fernández-Tardón, G, Subiza-Perez, M, Garcia-Aymerich, J, López-Vicente, M, Sunyer, J, Torrent, M, Ballester, F, Kelleher, C, Mehegan, J, Berg, AV, Herberth, G, Standl, M, Kuehni, CE, Pedersen, ESL, Jansen, M, Gehring, U, Boer, JMA, Devereux, G, Turner, S, Peltola, V, Lagström, H, Inskip, HM, Pike, KC, Dalmeijer, GW, Ent, CKVD & Thijs, C 2024, 'Physical activity, sedentary behaviour, and childhood asthma: a European collaborative analysis', BMJ Open Respiratory Research, bind 11, nr. 1, e001630. https://doi.org/10.1136/bmjresp-2023-001630

@article{2c2e835e2a0c4aecb4af60388a2ef3f0,

title = "Physical activity, sedentary behaviour, and childhood asthma: a European collaborative analysis",

abstract = "OBJECTIVES: To investigate the associations of physical activity (PA) and sedentary behaviour in early childhood with asthma and reduced lung function in later childhood within a large collaborative study.DESIGN: Pooling of longitudinal data from collaborating birth cohorts using meta-analysis of separate cohort-specific estimates and analysis of individual participant data of all cohorts combined.SETTING: Children aged 0-18 years from 26 European birth cohorts.PARTICIPANTS: 136 071 individual children from 26 cohorts, with information on PA and/or sedentary behaviour in early childhood and asthma assessment in later childhood.MAIN OUTCOME MEASURE: Questionnaire-based current asthma and lung function measured by spirometry (forced expiratory volume in 1 s (FEV1), FEV1/forced vital capacity) at age 6-18 years.RESULTS: Questionnaire-based and accelerometry-based PA and sedentary behaviour at age 3-5 years was not associated with asthma at age 6-18 years (PA in hours/day adjusted OR 1.01, 95% CI 0.98 to 1.04; sedentary behaviour in hours/day adjusted OR 1.03, 95% CI 0.99 to 1.07). PA was not associated with lung function at any age. Analyses of sedentary behaviour and lung function showed inconsistent results.CONCLUSIONS: Reduced PA and increased sedentary behaviour before 6 years of age were not associated with the presence of asthma later in childhood.",

keywords = "Humans, Child, Asthma/epidemiology, Sedentary Behavior, Adolescent, Male, Exercise, Child, Preschool, Europe/epidemiology, Female, Infant, Accelerometry, Longitudinal Studies, Surveys and Questionnaires, Forced Expiratory Volume, Spirometry, Infant, Newborn, Vital Capacity, Birth Cohort",

author = "Marianne Eijkemans and Monique Mommers and {Harskamp-van Ginkel}, {Margreet W} and Vrijkotte, {Tanja G M} and Johnny Ludvigsson and {\AA}shild Faresj{\"o} and Anna Bergstr{\"o}m and Sandra Ekstr{\"o}m and Veit Grote and Berthold Koletzko and Klaus B{\o}nnelykke and Eliasen, {Anders Ulrik} and Peter Bager and Mads Melbye and Isabella Annesi-Maesano and Nour Ba{\"i}z and Henrique Barros and Santos, {Ana Cristina} and Liesbeth Duijts and Mensink-Bout, {Sara M} and Claudia Flexeder and Sibylle Koletzko and Tamara Schikowski and Eggesb{\o}, {Merete {\AA}se} and Virissa Lenters and Guillermo Fern{\'a}ndez-Tard{\'o}n and Mikel Subiza-Perez and Judith Garcia-Aymerich and M{\'o}nica L{\'o}pez-Vicente and Jordi Sunyer and Maties Torrent and Ferran Ballester and Cecily Kelleher and John Mehegan and Berg, {Andrea von} and Gunda Herberth and Marie Standl and Kuehni, {Claudia E} and Pedersen, {Eva S L} and Maria Jansen and Ulrike Gehring and Boer, {Jolanda M A} and Graham Devereux and Steve Turner and Ville Peltola and Hanna Lagstr{\"o}m and Inskip, {Hazel M} and Pike, {Katharine C} and Dalmeijer, {Geertje W} and Ent, {Cornelis K van der} and Carel Thijs",

note = "{\textcopyright} Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.",

year = "2024",

month = aug,

day = "15",

doi = "10.1136/bmjresp-2023-001630",

language = "English",

volume = "11",

journal = "BMJ Open Respiratory Research",

issn = "2052-4439",

publisher = "BMJ Publishing Group",

number = "1",

}

TY - JOUR

T1 - Physical activity, sedentary behaviour, and childhood asthma

T2 - a European collaborative analysis

AU - Eijkemans, Marianne

AU - Mommers, Monique

AU - Harskamp-van Ginkel, Margreet W

AU - Vrijkotte, Tanja G M

AU - Ludvigsson, Johnny

AU - Faresjö, Åshild

AU - Bergström, Anna

AU - Ekström, Sandra

AU - Grote, Veit

AU - Koletzko, Berthold

AU - Bønnelykke, Klaus

AU - Eliasen, Anders Ulrik

AU - Bager, Peter

AU - Melbye, Mads

AU - Annesi-Maesano, Isabella

AU - Baïz, Nour

AU - Barros, Henrique

AU - Santos, Ana Cristina

AU - Duijts, Liesbeth

AU - Mensink-Bout, Sara M

AU - Flexeder, Claudia

AU - Koletzko, Sibylle

AU - Schikowski, Tamara

AU - Eggesbø, Merete Åse

AU - Lenters, Virissa

AU - Fernández-Tardón, Guillermo

AU - Subiza-Perez, Mikel

AU - Garcia-Aymerich, Judith

AU - López-Vicente, Mónica

AU - Sunyer, Jordi

AU - Torrent, Maties

AU - Ballester, Ferran

AU - Kelleher, Cecily

AU - Mehegan, John

AU - Berg, Andrea von

AU - Herberth, Gunda

AU - Standl, Marie

AU - Kuehni, Claudia E

AU - Pedersen, Eva S L

AU - Jansen, Maria

AU - Gehring, Ulrike

AU - Boer, Jolanda M A

AU - Devereux, Graham

AU - Turner, Steve

AU - Peltola, Ville

AU - Lagström, Hanna

AU - Inskip, Hazel M

AU - Pike, Katharine C

AU - Dalmeijer, Geertje W

AU - Ent, Cornelis K van der

AU - Thijs, Carel

PY - 2024/8/15

Y1 - 2024/8/15

N2 - OBJECTIVES: To investigate the associations of physical activity (PA) and sedentary behaviour in early childhood with asthma and reduced lung function in later childhood within a large collaborative study.DESIGN: Pooling of longitudinal data from collaborating birth cohorts using meta-analysis of separate cohort-specific estimates and analysis of individual participant data of all cohorts combined.SETTING: Children aged 0-18 years from 26 European birth cohorts.PARTICIPANTS: 136 071 individual children from 26 cohorts, with information on PA and/or sedentary behaviour in early childhood and asthma assessment in later childhood.MAIN OUTCOME MEASURE: Questionnaire-based current asthma and lung function measured by spirometry (forced expiratory volume in 1 s (FEV1), FEV1/forced vital capacity) at age 6-18 years.RESULTS: Questionnaire-based and accelerometry-based PA and sedentary behaviour at age 3-5 years was not associated with asthma at age 6-18 years (PA in hours/day adjusted OR 1.01, 95% CI 0.98 to 1.04; sedentary behaviour in hours/day adjusted OR 1.03, 95% CI 0.99 to 1.07). PA was not associated with lung function at any age. Analyses of sedentary behaviour and lung function showed inconsistent results.CONCLUSIONS: Reduced PA and increased sedentary behaviour before 6 years of age were not associated with the presence of asthma later in childhood.

AB - OBJECTIVES: To investigate the associations of physical activity (PA) and sedentary behaviour in early childhood with asthma and reduced lung function in later childhood within a large collaborative study.DESIGN: Pooling of longitudinal data from collaborating birth cohorts using meta-analysis of separate cohort-specific estimates and analysis of individual participant data of all cohorts combined.SETTING: Children aged 0-18 years from 26 European birth cohorts.PARTICIPANTS: 136 071 individual children from 26 cohorts, with information on PA and/or sedentary behaviour in early childhood and asthma assessment in later childhood.MAIN OUTCOME MEASURE: Questionnaire-based current asthma and lung function measured by spirometry (forced expiratory volume in 1 s (FEV1), FEV1/forced vital capacity) at age 6-18 years.RESULTS: Questionnaire-based and accelerometry-based PA and sedentary behaviour at age 3-5 years was not associated with asthma at age 6-18 years (PA in hours/day adjusted OR 1.01, 95% CI 0.98 to 1.04; sedentary behaviour in hours/day adjusted OR 1.03, 95% CI 0.99 to 1.07). PA was not associated with lung function at any age. Analyses of sedentary behaviour and lung function showed inconsistent results.CONCLUSIONS: Reduced PA and increased sedentary behaviour before 6 years of age were not associated with the presence of asthma later in childhood.

KW - Humans

KW - Child

KW - Asthma/epidemiology

KW - Sedentary Behavior

KW - Adolescent

KW - Male

KW - Exercise

KW - Child, Preschool

KW - Europe/epidemiology

KW - Female

KW - Infant

KW - Accelerometry

KW - Longitudinal Studies

KW - Surveys and Questionnaires

KW - Forced Expiratory Volume

KW - Spirometry

KW - Infant, Newborn

KW - Vital Capacity

KW - Birth Cohort

UR - http://www.scopus.com/inward/record.url?scp=85201519073&partnerID=8YFLogxK

U2 - 10.1136/bmjresp-2023-001630

DO - 10.1136/bmjresp-2023-001630

M3 - Journal article

C2 - 39147399

SN - 2052-4439

VL - 11

JO - BMJ Open Respiratory Research

JF - BMJ Open Respiratory Research

IS - 1

M1 - e001630

ER -

Physical activity, sedentary behaviour, and childhood asthma: a European collaborative analysis

Abstract

Adgang til dokumentet

Andre filer og links

Fingeraftryk

Citationsformater