Pharmacological modulation of the BOLD response: a study of acetazolamide and glyceryl trinitrate in humans

Mohammed Sohail Asghar; Adam E Hansen; Simon Pedersen; Henrik B W Larsson; Messoud Ashina

doi:10.1002/jmri.22659

Pharmacological modulation of the BOLD response: a study of acetazolamide and glyceryl trinitrate in humans

Mohammed Sohail Asghar, Adam E Hansen, Simon Pedersen, Henrik B W Larsson, Messoud Ashina

17 Citationer (Scopus)

Abstract

To examine the effect of acetazolamide, known to increase cerebral blood flow (CBF) and glyceryl trinitrate (GTN), known to increase cerebral blood volume (CBV) on the blood oxygenation level-dependent (BOLD) response in humans using 3 T magnetic resonance imaging (MRI), and to evaluate how pharmacological agents may modulate cerebral hemodynamic and thereby possibly the BOLD signal.

Originalsprog	Engelsk
Tidsskrift	Journal of Magnetic Resonance Imaging
Vol/bind	34
Udgave nummer	4
Sider (fra-til)	921-7
Antal sider	7
ISSN	1053-1807
DOI	https://doi.org/10.1002/jmri.22659
Status	Udgivet - 2011

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title = "Pharmacological modulation of the BOLD response: a study of acetazolamide and glyceryl trinitrate in humans",

abstract = "To examine the effect of acetazolamide, known to increase cerebral blood flow (CBF) and glyceryl trinitrate (GTN), known to increase cerebral blood volume (CBV) on the blood oxygenation level-dependent (BOLD) response in humans using 3 T magnetic resonance imaging (MRI), and to evaluate how pharmacological agents may modulate cerebral hemodynamic and thereby possibly the BOLD signal.",

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AU - Asghar, Mohammed Sohail

AU - Hansen, Adam E

AU - Pedersen, Simon

AU - Larsson, Henrik B W

AU - Ashina, Messoud

PY - 2011

Y1 - 2011

N2 - To examine the effect of acetazolamide, known to increase cerebral blood flow (CBF) and glyceryl trinitrate (GTN), known to increase cerebral blood volume (CBV) on the blood oxygenation level-dependent (BOLD) response in humans using 3 T magnetic resonance imaging (MRI), and to evaluate how pharmacological agents may modulate cerebral hemodynamic and thereby possibly the BOLD signal.

AB - To examine the effect of acetazolamide, known to increase cerebral blood flow (CBF) and glyceryl trinitrate (GTN), known to increase cerebral blood volume (CBV) on the blood oxygenation level-dependent (BOLD) response in humans using 3 T magnetic resonance imaging (MRI), and to evaluate how pharmacological agents may modulate cerebral hemodynamic and thereby possibly the BOLD signal.

UR - https://www.scopus.com/pages/publications/80052999653

U2 - 10.1002/jmri.22659

DO - 10.1002/jmri.22659

M3 - Journal article

C2 - 21769961

SN - 1053-1807

VL - 34

SP - 921

EP - 927

JO - Journal of Magnetic Resonance Imaging

JF - Journal of Magnetic Resonance Imaging

IS - 4

ER -

Pharmacological modulation of the BOLD response: a study of acetazolamide and glyceryl trinitrate in humans

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