PET/CT in the diagnosis of inflammatory bowel disease in pediatric patients: a review

Mikkel Malham Knudsen; S. Hess; R. G. Nielsen; S. Husby; P. F. Højlund-Carlsen

PET/CT in the diagnosis of inflammatory bowel disease in pediatric patients: a review

Mikkel Malham Knudsen, S. Hess, R. G. Nielsen, S. Husby, P. F. Højlund-Carlsen

Børne- og Ungeafdelingen

Abstrakt

The literature on positron emission tomography and computed tomography using 18fluoro-deoxyglusose (FDG-PET/CT) in the diagnosis of pediatric inflammatory bowel disease (IBD) is presented. Only five papers representing independent studies were identified and included in this review. Of these, two studies dealt with both stand-alone FDG-PET and FDG-PET/CT, while three were about stand-alone FDG-PET only. No studies could be found that focused on FDG-PET/CT only. The five studies comprised analysis of a total 181 pediatric patients (0-18 years of age). They unanimously indicated that FDG-PET/CT is a versatile method with a diagnostic high sensitivity ranging from 70% to 97%. In conclusion, the pediatric literature on FGD-PET/CT’s role in the diagnosis of IBD is very limited. Prospective studies of well characterized populations are needed in order to validate this novel imaging modality in pediatric IBD.

Keywords: Inflammatory bowel disease, ulcerative colitis, Crohn’s disease, positron-emission tomography and computed tomography

Originalsprog	Engelsk
Tidsskrift	American Journal of Nuclear Medicine and Molecular Imaging
Sider (fra-til)	225
Antal sider	230
ISSN	2160-8407
Status	Udgivet - 2014

Citationsformater

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title = "PET/CT in the diagnosis of inflammatory bowel disease in pediatric patients: a review",

abstract = "The literature on positron emission tomography and computed tomography using 18fluoro-deoxyglusose (FDG-PET/CT) in the diagnosis of pediatric inflammatory bowel disease (IBD) is presented. Only five papers representing independent studies were identified and included in this review. Of these, two studies dealt with both stand-alone FDG-PET and FDG-PET/CT, while three were about stand-alone FDG-PET only. No studies could be found that focused on FDG-PET/CT only. The five studies comprised analysis of a total 181 pediatric patients (0-18 years of age). They unanimously indicated that FDG-PET/CT is a versatile method with a diagnostic high sensitivity ranging from 70% to 97%. In conclusion, the pediatric literature on FGD-PET/CT{\textquoteright}s role in the diagnosis of IBD is very limited. Prospective studies of well characterized populations are needed in order to validate this novel imaging modality in pediatric IBD.Keywords: Inflammatory bowel disease, ulcerative colitis, Crohn{\textquoteright}s disease, positron-emission tomography and computed tomography",

author = "Knudsen, {Mikkel Malham} and S. Hess and Nielsen, {R. G.} and S. Husby and H{\o}jlund-Carlsen, {P. F.}",

year = "2014",

language = "English",

pages = "225",

journal = "American Journal of Nuclear Medicine and Molecular Imaging",

issn = "2160-8407",

publisher = "E-Century Publishing Corporation",

}

TY - JOUR

T1 - PET/CT in the diagnosis of inflammatory bowel disease in pediatric patients: a review

AU - Knudsen, Mikkel Malham

AU - Hess, S.

AU - Nielsen, R. G.

AU - Husby, S.

AU - Højlund-Carlsen, P. F.

PY - 2014

Y1 - 2014

N2 - The literature on positron emission tomography and computed tomography using 18fluoro-deoxyglusose (FDG-PET/CT) in the diagnosis of pediatric inflammatory bowel disease (IBD) is presented. Only five papers representing independent studies were identified and included in this review. Of these, two studies dealt with both stand-alone FDG-PET and FDG-PET/CT, while three were about stand-alone FDG-PET only. No studies could be found that focused on FDG-PET/CT only. The five studies comprised analysis of a total 181 pediatric patients (0-18 years of age). They unanimously indicated that FDG-PET/CT is a versatile method with a diagnostic high sensitivity ranging from 70% to 97%. In conclusion, the pediatric literature on FGD-PET/CT’s role in the diagnosis of IBD is very limited. Prospective studies of well characterized populations are needed in order to validate this novel imaging modality in pediatric IBD.Keywords: Inflammatory bowel disease, ulcerative colitis, Crohn’s disease, positron-emission tomography and computed tomography

AB - The literature on positron emission tomography and computed tomography using 18fluoro-deoxyglusose (FDG-PET/CT) in the diagnosis of pediatric inflammatory bowel disease (IBD) is presented. Only five papers representing independent studies were identified and included in this review. Of these, two studies dealt with both stand-alone FDG-PET and FDG-PET/CT, while three were about stand-alone FDG-PET only. No studies could be found that focused on FDG-PET/CT only. The five studies comprised analysis of a total 181 pediatric patients (0-18 years of age). They unanimously indicated that FDG-PET/CT is a versatile method with a diagnostic high sensitivity ranging from 70% to 97%. In conclusion, the pediatric literature on FGD-PET/CT’s role in the diagnosis of IBD is very limited. Prospective studies of well characterized populations are needed in order to validate this novel imaging modality in pediatric IBD.Keywords: Inflammatory bowel disease, ulcerative colitis, Crohn’s disease, positron-emission tomography and computed tomography

M3 - Journal article

SP - 225

JO - American Journal of Nuclear Medicine and Molecular Imaging

JF - American Journal of Nuclear Medicine and Molecular Imaging

SN - 2160-8407

ER -