PET/CT in the diagnosis of inflammatory bowel disease in pediatric patients: a review

Mikkel Malham, Søren Hess, Rasmus G Nielsen, Steffen Husby, Poul Flemming Høilund-Carlsen


The literature on positron emission tomography and computed tomography using 18fluoro-deoxyglusose (FDG-PET/CT) in the diagnosis of pediatric inflammatory bowel disease (IBD) is presented. Only five papers representing independent studies were identified and included in this review. Of these, two studies dealt with both stand-alone FDG-PET and FDG-PET/CT, while three were about stand-alone FDG-PET only. No studies could be found that focused on FDG-PET/CT only. The five studies comprised analysis of a total 181 pediatric patients (0-18 years of age). They unanimously indicated that FDG-PET/CT is a versatile method with a diagnostic high sensitivity ranging from 70% to 97%. In conclusion, the pediatric literature on FGD-PET/CT’s role in the diagnosis of IBD is very limited. Prospective studies of well characterized populations are needed in order to validate this novel imaging modality in pediatric IBD.

Keywords: Inflammatory bowel disease, ulcerative colitis, Crohn’s disease, positron-emission tomography and computed tomography
TidsskriftAmerican Journal of Nuclear Medicine and Molecular Imaging
Udgave nummer3
Sider (fra-til)225-30
Antal sider6
StatusUdgivet - 2014
Udgivet eksterntJa