PET med amyloidligander bør ikke anvendesrutinemæssigt i tidlig diagnostik af Alzheimerssygdom – en gennemgang af et Cochranereview

1 Citationer (Scopus)

Abstract

Recent diagnostic criteria for Alzheimer's disease incorporate biomarkers in order to increase the diagnostic accuracy. In a recent Cochrane review the ligand (11)C-PiB showed a high sensitivity, but low specificity for detecting patients with mild cognitive impairment who would develop Alzheimer's dementia. Given the evolution of Alzheimer pathology, these findings are not surprising. With current limited treatment options for MCI, (11)C-PiB-PET cannot be recommended for routine use in MCI and should be used only in selected cases where a positive scan will alter management.

Bidragets oversatte titelPET with amyloid ligands should not be applied routinely in early diagnostics of Alzheimer's disease
OriginalsprogDansk
ArtikelnummerV11140610
TidsskriftUgeskrift for Laeger
Vol/bind177
Udgave nummer32
Sider (fra-til)1515-1517
Antal sider3
ISSN0041-5782
StatusUdgivet - 3 aug. 2015

Fingeraftryk

Dyk ned i forskningsemnerne om 'PET med amyloidligander bør ikke anvendesrutinemæssigt i tidlig diagnostik af Alzheimerssygdom – en gennemgang af et Cochranereview'. Sammen danner de et unikt fingeraftryk.

Citationsformater