Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Persistent organic pollutants and penile bone mineral density in East Greenland and Canadian polar bears (Ursus maritimus) during 1996-2015

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Long-term wind turbine noise exposure and the risk of incident atrial fibrillation in the Danish Nurse cohort

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Variations in repeated serum concentrations of UV filters, phthalates, phenols and parabens during pregnancy

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Long-term wind turbine noise exposure and the risk of incident atrial fibrillation in the Danish Nurse cohort

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Long-term wind turbine noise exposure and incidence of myocardial infarction in the Danish nurse cohort

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Environmental grass pollen levels in utero and at birth and cord blood IgE: Analysis of three birth cohorts

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. What brings meaning to life in a highly secular society? A study on sources of meaning among Danes

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Fracture risk in women with type II diabetes. Results from a historical cohort with fracture follow-up

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

Persistent organic pollutants (POPs) are long-range transported to the Arctic via atmospheric and oceanic currents, where they biomagnify to high concentrations in the tissues of apex predators such as polar bears (Ursus maritimus). A major concern of POP exposure is their physiological effects on vital organ-tissues posing a threat to the health and survival of polar bears. Here we examined the relationship between selected POPs and baculum bone mineral density (BMD) in the East Greenland and seven Canadian subpopulations of polar bears. BMD was examined in 471 bacula collected between years 1996-2015 while POP concentrations in adipose tissue were determined in 67-192 of these individuals collected from 1999 to -2015. A geographical comparison showed that baculum BMD was significantly lowest in polar bears from East Greenland (EG) when compared to Gulf of Boothia (GB), Southern Hudson (SH) and Western Hudson (WH) Bay subpopulations (all p < 0.05). The calculation of a T-score osteoporosis index for the EG subpopulation using WH bears as a reference group gave a T-score of -1.44 which indicate risk of osteopenia. Concentrations of ΣPCB74(polychlorinated biphenyls), ΣDDT3(dichlorodiphenyltrichloroethanes), p,p'-DDE (dichlorodiphenyldichloroethylene), ΣHCH3(hexachlorohexane) and α-HCH was significantly highest in EG bears while ΣPBDE (polybrominated diphenyl ethers), BDE-47 and BDE-153 was significantly highest in SH bears (all p < 0.04). Statistical analyses of individual baculum BMD vs. POP concentrations showed that BMD was positively correlated with ΣPCB74, CB-153, HCB (hexachlorobenzene), ΣHCH, β-HCH, ClBz (chlorobenzene), ΣPBDE and BDE-153 (all p < 0.03). In conclusion, baculum density was significantly lowest in East Greenland polar bears despite the positive statistical correlations of BMD vs. POPs. Other important factors such as nutritional status, body mass and body condition was not available for the statistical modelling. Since on-going environmental changes are known to affect these, future studies need to incorporate nutritional, endocrine and genetic parameters to further understand how POP exposure may disrupt bone homeostasis and affect baculum BMD across polar bear subpopulations.

OriginalsprogEngelsk
TidsskriftEnvironmental International
Vol/bind114
Sider (fra-til)212-218
Antal sider7
ISSN0160-4120
DOI
StatusUdgivet - mar. 2018

ID: 53543355