Abstract
Numerous studies have shown that perioperative heparin bridging in patients treated with a vitamin K antagonist leads to an increased incidence of bleeding and so far, there is no evidence that it leads to a significant reduction in postoperative thromboembolism as summarised in this review. Prophylactic dosage of heparin is recommended after major surgery. Heparin bridging is not relevant in patients receiving a direct oral anticoagulant due to the rapid onset and offset of action of DOACs.
Originalsprog | Engelsk |
---|---|
Tidsskrift | Ugeskrift for Laeger |
Vol/bind | 183 |
Udgave nummer | 47 |
ISSN | 0041-5782 |
Status | Udgivet - 22 nov. 2021 |
Emneord
- Anticoagulants/adverse effects
- Hemorrhage
- Heparin/adverse effects
- Humans
- Perioperative Care
- Thromboembolism/prevention & control
- Vitamin K