Perioperative heparin bridging is rarely indicated

Abstract

Numerous studies have shown that perioperative heparin bridging in patients treated with a vitamin K antagonist leads to an increased incidence of bleeding and so far, there is no evidence that it leads to a significant reduction in postoperative thromboembolism as summarised in this review. Prophylactic dosage of heparin is recommended after major surgery. Heparin bridging is not relevant in patients receiving a direct oral anticoagulant due to the rapid onset and offset of action of DOACs.

OriginalsprogEngelsk
TidsskriftUgeskrift for Laeger
Vol/bind183
Udgave nummer47
ISSN0041-5782
StatusUdgivet - 22 nov. 2021

Emneord

  • Anticoagulants/adverse effects
  • Hemorrhage
  • Heparin/adverse effects
  • Humans
  • Perioperative Care
  • Thromboembolism/prevention & control
  • Vitamin K

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