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Perioperative Colonic Evaluation in Patients with Rectal Cancer; MR Colonography Versus Standard Care

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@article{5c5b23b3bb5d46fb9d6845ecdb4e600f,
title = "Perioperative Colonic Evaluation in Patients with Rectal Cancer; MR Colonography Versus Standard Care",
abstract = "RATIONALE AND OBJECTIVES: Preoperative colonic evaluation is often inadequate because of cancer stenosis making a full conventional colonoscopy (CC) impossible. In several studies, cancer stenosis has been shown in up to 16%-34% of patients with colorectal cancer. The purpose of this study was to prospectively evaluate the completion rate of preoperative colonic evaluation and the quality of perioperative colonic evaluation using magnetic resonance colonography (MRC) in patients with rectal cancer.MATERIALS AND METHODS: Patients diagnosed with rectal cancer were randomized to either group A: standard preoperative diagnostic work-up or group B: preoperative MR diagnostic work-up (standard preoperative diagnostic work-up + MRC). A complete and adequate perioperative clean-colon evaluation (PCE) was defined as either a complete preoperative colonic evaluation or a complete colonic evaluation within 3 months postoperatively.RESULTS: Twenty-eight patients were randomized to group A and 28 to group B. Complete preoperative colonic evaluation with CC was achieved in 39% patients in group A and 93% for group B (Fisher's exact test, P < .001). PCE with CC was achieved in 64% and 93% in groups A and B, respectively (Fisher's exact test, P = .02). In group A, one synchronous cancer was found by CC. However, the location was misjudged as a sigmoid cancer. In group B, two synchronous cancers were found in the same patient who had an insufficient preoperative CC due to an obstructing rectal cancer.CONCLUSIONS: MRC is a valuable tool and is recommended as part of the standard preoperative evaluation for patients with rectal cancer.",
author = "Achiam, {Michael Patrick} and Vibeke L{\o}gager and Vera Lund-Rasmussen and Cecilie Okholm and Talie Mollerup and Thomsen, {Henrik S} and Jacob Rosenberg",
note = "Copyright {\textcopyright} 2015 AUR. Published by Elsevier Inc. All rights reserved.",
year = "2015",
month = dec,
doi = "10.1016/j.acra.2015.08.019",
language = "English",
volume = "22",
pages = "1522--8",
journal = "Academic Radiology",
issn = "1076-6332",
publisher = "Elsevier BV",
number = "12",

}

RIS

TY - JOUR

T1 - Perioperative Colonic Evaluation in Patients with Rectal Cancer; MR Colonography Versus Standard Care

AU - Achiam, Michael Patrick

AU - Løgager, Vibeke

AU - Lund-Rasmussen, Vera

AU - Okholm, Cecilie

AU - Mollerup, Talie

AU - Thomsen, Henrik S

AU - Rosenberg, Jacob

N1 - Copyright © 2015 AUR. Published by Elsevier Inc. All rights reserved.

PY - 2015/12

Y1 - 2015/12

N2 - RATIONALE AND OBJECTIVES: Preoperative colonic evaluation is often inadequate because of cancer stenosis making a full conventional colonoscopy (CC) impossible. In several studies, cancer stenosis has been shown in up to 16%-34% of patients with colorectal cancer. The purpose of this study was to prospectively evaluate the completion rate of preoperative colonic evaluation and the quality of perioperative colonic evaluation using magnetic resonance colonography (MRC) in patients with rectal cancer.MATERIALS AND METHODS: Patients diagnosed with rectal cancer were randomized to either group A: standard preoperative diagnostic work-up or group B: preoperative MR diagnostic work-up (standard preoperative diagnostic work-up + MRC). A complete and adequate perioperative clean-colon evaluation (PCE) was defined as either a complete preoperative colonic evaluation or a complete colonic evaluation within 3 months postoperatively.RESULTS: Twenty-eight patients were randomized to group A and 28 to group B. Complete preoperative colonic evaluation with CC was achieved in 39% patients in group A and 93% for group B (Fisher's exact test, P < .001). PCE with CC was achieved in 64% and 93% in groups A and B, respectively (Fisher's exact test, P = .02). In group A, one synchronous cancer was found by CC. However, the location was misjudged as a sigmoid cancer. In group B, two synchronous cancers were found in the same patient who had an insufficient preoperative CC due to an obstructing rectal cancer.CONCLUSIONS: MRC is a valuable tool and is recommended as part of the standard preoperative evaluation for patients with rectal cancer.

AB - RATIONALE AND OBJECTIVES: Preoperative colonic evaluation is often inadequate because of cancer stenosis making a full conventional colonoscopy (CC) impossible. In several studies, cancer stenosis has been shown in up to 16%-34% of patients with colorectal cancer. The purpose of this study was to prospectively evaluate the completion rate of preoperative colonic evaluation and the quality of perioperative colonic evaluation using magnetic resonance colonography (MRC) in patients with rectal cancer.MATERIALS AND METHODS: Patients diagnosed with rectal cancer were randomized to either group A: standard preoperative diagnostic work-up or group B: preoperative MR diagnostic work-up (standard preoperative diagnostic work-up + MRC). A complete and adequate perioperative clean-colon evaluation (PCE) was defined as either a complete preoperative colonic evaluation or a complete colonic evaluation within 3 months postoperatively.RESULTS: Twenty-eight patients were randomized to group A and 28 to group B. Complete preoperative colonic evaluation with CC was achieved in 39% patients in group A and 93% for group B (Fisher's exact test, P < .001). PCE with CC was achieved in 64% and 93% in groups A and B, respectively (Fisher's exact test, P = .02). In group A, one synchronous cancer was found by CC. However, the location was misjudged as a sigmoid cancer. In group B, two synchronous cancers were found in the same patient who had an insufficient preoperative CC due to an obstructing rectal cancer.CONCLUSIONS: MRC is a valuable tool and is recommended as part of the standard preoperative evaluation for patients with rectal cancer.

U2 - 10.1016/j.acra.2015.08.019

DO - 10.1016/j.acra.2015.08.019

M3 - Journal article

C2 - 26391858

VL - 22

SP - 1522

EP - 1528

JO - Academic Radiology

JF - Academic Radiology

SN - 1076-6332

IS - 12

ER -

ID: 45793845