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Region Hovedstaden - en del af Københavns Universitetshospital
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Perfluorinated substances, risk factors for multiple sclerosis and cellular immune activation

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. MAIT cell subtypes in multiple sclerosis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Antibodies to Epstein-Barr virus and neurotropic viruses in multiple sclerosis and optic neuritis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. B cells from patients with multiple sclerosis have a pathogenic phenotype and increased LTα and TGFβ1 response

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Inflammatory markers of CHMP2B-mediated frontotemporal dementia

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Initial high-efficacy disease-modifying therapy in multiple sclerosis: A nationwide cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Validation of suPAR turbidimetric assay on Cobas® (c502 and c702) and comparison to suPAR ELISA

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. MAIT cell subtypes in multiple sclerosis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Early Intrathecal T Helper 17.1 Cell Activity in Huntington Disease

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

Perfluorinated alkylated substances (PFASs) have immunomodulatory effects but the impact on multiple sclerosis (MS) and cellular immune functions is only sparsely described. In the present study, we found lower concentrations of the long chain PFAS perfluorooctane sulfonic acid (PFOS) in MS than in healthy controls (HC). In HC, we did not detect associations between PFOS concentrations and immune phenotypes. Analyzing the impact of known MS risk factors on cellular immune functions, we found that smoking and Epstein-Barr nuclear antigen 1 antibodies were associated with distinct circulating immune cell changes. In summary, current background PFAS exposure is not an important risk factor for MS.

OriginalsprogEngelsk
TidsskriftJournal of Neuroimmunology
Vol/bind330
Sider (fra-til)90-95
Antal sider6
ISSN0165-5728
DOI
StatusUdgivet - 15 maj 2019

Bibliografisk note

Copyright © 2019 Elsevier B.V. All rights reserved.

ID: 58576743