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Patients with polymyositis show changes in muscle protein charges

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Vis graf over relationer
Polymyositis (PM) appears with indolent proximal muscle weakness and is an inflammatory disease with breakdown of muscle cells. In our study the protein charge concentrations of the contractile proteins in the A and I bands were determined, applying a microelectrode technique. Patients with PM show a lower protein charge concentration than healthy control subjects which may be caused by the breakdown and removal of the proteins in the contractile filaments. A tool to judge the state of the disease as well as an aid in diagnosis may have been found in this method.
OriginalsprogEngelsk
TidsskriftJournal of Rheumatology
Vol/bind16
Udgave nummer12
Sider (fra-til)1542-4
Antal sider3
ISSN0315-162X
StatusUdgivet - dec. 1989

ID: 42808862