TY - JOUR
T1 - Patient and public involvement in contemporary large intensive care trials
T2 - Protocol for a meta-epidemiological study
AU - Barot, Emily
AU - Kjaer, Maj-Brit Nørregaard
AU - Collet, Marie
AU - Crescioli, Elena
AU - Rasmussen, Bodil Steen
AU - Estrup, Stine
AU - Mortensen, Camilla Bekker
AU - Vesterlund, Gitte Kingo
AU - Sivapalan, Praleene
AU - Anthon, Carl Thomas
AU - Bruun, Camilla Rahbek Lysholm
AU - Poulsen, Lone Musaeus
AU - Møller, Morten Hylander
AU - Perner, Anders
AU - Granholm, Anders
N1 - © 2021 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.
PY - 2021/10
Y1 - 2021/10
N2 - BACKGROUND: Patient and public involvement (PPI) in randomized clinical trials (RCTs) has increased in recent years but remains the exception rather than the rule. We aim to assess the frequency and extent of PPI in large, contemporary RCTs conducted in an intensive care setting.METHODS AND DESIGN: We will conduct a meta-epidemiological study of RCTs conducted in intensive care settings published since 2019 and assess their use of PPI. We will extract trial characteristics and verify the use of PPI with trial authors unless specifically stated in the published paper. The primary outcome will be the proportion of trials that use PPI. Secondary outcomes will explore which groups are consulted, at which stage of the trial process this occurs, and by what means these opinions are collected and implemented.DISCUSSION: This meta-epidemiological study will provide an important insight into the use of PPI in large, contemporary intensive care trials. We wish to reveal ways in which patient involvement could be incorporated more broadly and purposefully here and help to empower clinicians, researchers and patients to collaborate further on future research processes and goals.
AB - BACKGROUND: Patient and public involvement (PPI) in randomized clinical trials (RCTs) has increased in recent years but remains the exception rather than the rule. We aim to assess the frequency and extent of PPI in large, contemporary RCTs conducted in an intensive care setting.METHODS AND DESIGN: We will conduct a meta-epidemiological study of RCTs conducted in intensive care settings published since 2019 and assess their use of PPI. We will extract trial characteristics and verify the use of PPI with trial authors unless specifically stated in the published paper. The primary outcome will be the proportion of trials that use PPI. Secondary outcomes will explore which groups are consulted, at which stage of the trial process this occurs, and by what means these opinions are collected and implemented.DISCUSSION: This meta-epidemiological study will provide an important insight into the use of PPI in large, contemporary intensive care trials. We wish to reveal ways in which patient involvement could be incorporated more broadly and purposefully here and help to empower clinicians, researchers and patients to collaborate further on future research processes and goals.
KW - Critical Care
KW - Epidemiologic Studies
KW - Humans
KW - Patient Participation
KW - Research Personnel
UR - http://www.scopus.com/inward/record.url?scp=85112325872&partnerID=8YFLogxK
U2 - 10.1111/aas.13953
DO - 10.1111/aas.13953
M3 - Review
C2 - 34273181
VL - 65
SP - 1351
EP - 1354
JO - Acta Anaesthesiologica Scandinavica
JF - Acta Anaesthesiologica Scandinavica
SN - 0001-5172
IS - 9
ER -