Parenteral estrogen versus combined androgen deprivation in the treatment of metastatic prostatic cancer -- Scandinavian Prostatic Cancer Group (SPCG) Study No. 5

Per Olov Hedlund; Martti Ala-Opas; Einar Brekkan; Jan Erik Damber; Lena Damber; Inger Hagerman; Svein Haukaas; Peter Henriksson; Peter Iversen; Ake Pousette; Finn Rasmussen; Jaakko Salo; Sigmund Vaage; Eberhard Varenhorst; Scandinavian Prostatic Cancer Group

doi:10.1080/003655902762467549

Parenteral estrogen versus combined androgen deprivation in the treatment of metastatic prostatic cancer -- Scandinavian Prostatic Cancer Group (SPCG) Study No. 5

Per Olov Hedlund, Martti Ala-Opas, Einar Brekkan, Jan Erik Damber, Lena Damber, Inger Hagerman, Svein Haukaas, Peter Henriksson, Peter Iversen, Ake Pousette, Finn Rasmussen, Jaakko Salo, Sigmund Vaage, Eberhard Varenhorst, Scandinavian Prostatic Cancer Group

48 Citationer (Scopus)

Abstract

In the mid-1980s, interest in parenteral estrogen therapy for prostate cancer was renewed when it was found that it influenced liver metabolism only marginally and had very few cardiovascular side-effects. In this study high-dose polyestradiol phosphate (PEP; Estradurin) was compared to combined androgen deprivation (CAD) for the treatment of patients with metastatic prostate cancer. The aim of the study was to compare anticancer efficacy and adverse events, especially cardiovascular side-effects.

Originalsprog	Engelsk
Tidsskrift	Scandinavian Journal of Urology and Nephrology
Vol/bind	36
Udgave nummer	6
Sider (fra-til)	405-13
Antal sider	9
ISSN	0036-5599
DOI	https://doi.org/10.1080/003655902762467549
Status	Udgivet - 1 jan. 2002

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10.1080/003655902762467549

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Hedlund, P. O., Ala-Opas, M., Brekkan, E., Damber, J. E., Damber, L., Hagerman, I., Haukaas, S., Henriksson, P., Iversen, P., Pousette, A., Rasmussen, F., Salo, J., Vaage, S., Varenhorst, E., & Scandinavian Prostatic Cancer Group (2002). Parenteral estrogen versus combined androgen deprivation in the treatment of metastatic prostatic cancer -- Scandinavian Prostatic Cancer Group (SPCG) Study No. 5. Scandinavian Journal of Urology and Nephrology, 36(6), 405-13. https://doi.org/10.1080/003655902762467549

Parenteral estrogen versus combined androgen deprivation in the treatment of metastatic prostatic cancer -- Scandinavian Prostatic Cancer Group (SPCG) Study No. 5. / Hedlund, Per Olov; Ala-Opas, Martti; Brekkan, Einar et al.
I: Scandinavian Journal of Urology and Nephrology, Bind 36, Nr. 6, 01.01.2002, s. 405-13.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning

Hedlund, PO, Ala-Opas, M, Brekkan, E, Damber, JE, Damber, L, Hagerman, I, Haukaas, S, Henriksson, P, Iversen, P, Pousette, A, Rasmussen, F, Salo, J, Vaage, S, Varenhorst, E & Scandinavian Prostatic Cancer Group 2002, 'Parenteral estrogen versus combined androgen deprivation in the treatment of metastatic prostatic cancer -- Scandinavian Prostatic Cancer Group (SPCG) Study No. 5', Scandinavian Journal of Urology and Nephrology, bind 36, nr. 6, s. 405-13. https://doi.org/10.1080/003655902762467549

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abstract = "In the mid-1980s, interest in parenteral estrogen therapy for prostate cancer was renewed when it was found that it influenced liver metabolism only marginally and had very few cardiovascular side-effects. In this study high-dose polyestradiol phosphate (PEP; Estradurin) was compared to combined androgen deprivation (CAD) for the treatment of patients with metastatic prostate cancer. The aim of the study was to compare anticancer efficacy and adverse events, especially cardiovascular side-effects.",

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AU - Damber, Jan Erik

AU - Damber, Lena

AU - Hagerman, Inger

AU - Haukaas, Svein

AU - Henriksson, Peter

AU - Iversen, Peter

AU - Pousette, Ake

AU - Rasmussen, Finn

AU - Salo, Jaakko

AU - Vaage, Sigmund

AU - Varenhorst, Eberhard

AU - Scandinavian Prostatic Cancer Group

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Parenteral estrogen versus combined androgen deprivation in the treatment of metastatic prostatic cancer -- Scandinavian Prostatic Cancer Group (SPCG) Study No. 5

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