Overestimated lead times in cancer screening has led to substantial underestimation of overdiagnosis

P-H Zahl; Karsten Juhl Jørgensen; P C Gøtzsche

doi:10.1038/bjc.2013.427

Overestimated lead times in cancer screening has led to substantial underestimation of overdiagnosis

P-H Zahl, Karsten Juhl Jørgensen, P C Gøtzsche

77 Citationer (Scopus)

Abstract

Published lead time estimates in breast cancer screening vary from 1 to 7 years and the percentages of overdiagnosis vary from 0 to 75%. The differences are usually explained as random variations. We study how much can be explained by using different definitions and methods.

Originalsprog	Engelsk
Tidsskrift	B J C
Vol/bind	109
Udgave nummer	7
Sider (fra-til)	2014-9
Antal sider	6
ISSN	0007-0920
DOI	https://doi.org/10.1038/bjc.2013.427
Status	Udgivet - 1 okt. 2013

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10.1038/bjc.2013.427

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title = "Overestimated lead times in cancer screening has led to substantial underestimation of overdiagnosis",

abstract = "Published lead time estimates in breast cancer screening vary from 1 to 7 years and the percentages of overdiagnosis vary from 0 to 75%. The differences are usually explained as random variations. We study how much can be explained by using different definitions and methods.",

keywords = "Aged, Breast Neoplasms, Diagnostic Errors, Early Detection of Cancer, Female, Humans, Incidence, Mammography, Mass Screening, Middle Aged",

author = "P-H Zahl and {Juhl J{\o}rgensen}, Karsten and G{\o}tzsche, {P C}",

year = "2013",

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doi = "10.1038/bjc.2013.427",

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T1 - Overestimated lead times in cancer screening has led to substantial underestimation of overdiagnosis

AU - Zahl, P-H

AU - Juhl Jørgensen, Karsten

AU - Gøtzsche, P C

PY - 2013/10/1

Y1 - 2013/10/1

N2 - Published lead time estimates in breast cancer screening vary from 1 to 7 years and the percentages of overdiagnosis vary from 0 to 75%. The differences are usually explained as random variations. We study how much can be explained by using different definitions and methods.

AB - Published lead time estimates in breast cancer screening vary from 1 to 7 years and the percentages of overdiagnosis vary from 0 to 75%. The differences are usually explained as random variations. We study how much can be explained by using different definitions and methods.

KW - Aged

KW - Breast Neoplasms

KW - Diagnostic Errors

KW - Early Detection of Cancer

KW - Female

KW - Humans

KW - Incidence

KW - Mammography

KW - Mass Screening

KW - Middle Aged

U2 - 10.1038/bjc.2013.427

DO - 10.1038/bjc.2013.427

M3 - Journal article

C2 - 23963144

SN - 0007-0920

VL - 109

SP - 2014

EP - 2019

JO - B J C

JF - B J C

IS - 7

ER -

Overestimated lead times in cancer screening has led to substantial underestimation of overdiagnosis

Abstract

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