Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Outcomes of monoamniotic twin pregnancies managed primarily in outpatient care-A Danish multicenter study

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Human papilloma virus vaccination and its real-life efficacy

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Current use of noninvasive prenatal testing in Europe, Australia and the USA: A graphical presentation

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Implementation of exome sequencing in fetal diagnostics - data and experiences from a tertiary center in Denmark

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. "It's probably nothing, but…" Couples' experiences of pregnancy following an uncertain prenatal genetic result

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Non-invasive prenatal testing and maternal obesity - A review

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  1. Fetal fraction of cell-free DNA in pregnancies after fresh or frozen embryo transfer following assisted reproductive technologies

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Current use of noninvasive prenatal testing in Europe, Australia and the USA: A graphical presentation

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Implementation of exome sequencing in fetal diagnostics - data and experiences from a tertiary center in Denmark

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. "It's probably nothing, but…" Couples' experiences of pregnancy following an uncertain prenatal genetic result

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

INTRODUCTION: Monoamniotic twin pregnancies are high-risk pregnancies, and management by inpatient or frequent outpatient care is recommended. We report the outcomes of a national cohort of monoamniotic twin pregnancies managed primarily as outpatients MATERIAL AND METHODS: We analyzed prospectively recorded data from the Danish Fetal Medicine Database, local databases, and medical records of all monoamniotic twin pregnancies diagnosed at the first trimester scan or later, and managed at the six major fetal medicine centers in Denmark over a 10 year period RESULTS: Sixty-one monoamniotic twin pregnancies were included. Thirteen pregnancies were terminated early. Of the remaining 48 pregnancies with a normal first trimester scan, there were 36 fetal losses (25 spontaneous miscarriages <22+0 weeks, three late terminations and eight intrauterine deaths >22 weeks) and 60 live-born children (62.5%), all of whom were delivered by cesarean delivery at a median gestational age of 33+0 weeks. Three children had minor malformations and there was one pregnancy with twin-to-twin-transfusion-syndrome. After 26+0 weeks, 78.8% were managed as outpatients. Intrauterine death occurred in 3.8% of outpatients and in 28.6% of inpatients (admitted due to complications). At weeks 32, 33, and 34, the prospective risk of intrauterine death was 6.9%, 4.2%, and 5.9%, respectively CONCLUSION: In this nationwide, unselected population, only 62.5% of fetuses with a normal first trimester scan were born alive. In contrast, the mortality was 3.8% after 26 weeks among the 78.8% of the cohort that was managed as outpatients. More knowledge is still needed to predict which pregnancies are at the highest risk of intrauterine death. This article is protected by copyright. All rights reserved.

OriginalsprogEngelsk
TidsskriftActa Obstetricia et Gynecologica Scandinavica
Vol/bind98
Udgave nummer4
Sider (fra-til)479-486
Antal sider8
ISSN0001-6349
DOI
StatusUdgivet - apr. 2019

ID: 55722043