TY - JOUR
T1 - Outcome of patients with low-gradient "severe" aortic stenosis and preserved ejection fraction
AU - Jander, Nikolaus
AU - Minners, Jan
AU - Holme, Ingar
AU - Gerdts, Eva
AU - Boman, Kurt
AU - Brudi, Philippe
AU - Chambers, John B
AU - Egstrup, Kenneth
AU - Kesäniemi, Y Antero
AU - Malbecq, William
AU - Nienaber, Christoph A
AU - Ray, Simon
AU - Rossebø, Anne
AU - Pedersen, Terje
AU - Skjærpe, Terje
AU - Willenheimer, Ronnie
AU - Wachtell, Kristian
AU - Neumann, Franz-Josef
AU - Gohlke-Bärwolf, Christa
PY - 2011/3/1
Y1 - 2011/3/1
N2 - Retrospective studies have suggested that patients with a low transvalvular gradient in the presence of an aortic valve area <1.0 cm² and normal ejection fraction may represent a subgroup with an advanced stage of aortic valve disease, reduced stroke volume, and poor prognosis requiring early surgery. We therefore evaluated the outcome of patients with low-gradient "severe" stenosis (defined as aortic valve area <1.0 cm² and mean gradient ≤ 40 mm Hg) in the prospective Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) study.
AB - Retrospective studies have suggested that patients with a low transvalvular gradient in the presence of an aortic valve area <1.0 cm² and normal ejection fraction may represent a subgroup with an advanced stage of aortic valve disease, reduced stroke volume, and poor prognosis requiring early surgery. We therefore evaluated the outcome of patients with low-gradient "severe" stenosis (defined as aortic valve area <1.0 cm² and mean gradient ≤ 40 mm Hg) in the prospective Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) study.
U2 - 10.1161/CIRCULATIONAHA.110.983510
DO - 10.1161/CIRCULATIONAHA.110.983510
M3 - Journal article
C2 - 21321152
SN - 0009-7322
VL - 123
SP - 887
EP - 895
JO - Circulation (Baltimore)
JF - Circulation (Baltimore)
IS - 8
ER -