Osteogenic protein 1 device increases bone formation and bone graft resorption around cementless implants

Thomas B Jensen; Søren Overgaard; Martin Lind; Ole Rahbek; Cody Bünger; Kjeld Søballe

doi:10.1080/000164702317281378

Osteogenic protein 1 device increases bone formation and bone graft resorption around cementless implants

Thomas B Jensen, Søren Overgaard, Martin Lind, Ole Rahbek, Cody Bünger, Kjeld Søballe

55 Citationer (Scopus)

Abstract

In each femoral condyle of 8 Labrador dogs, a non weight-bearing hydroxyapatite-coated implant was inserted surrounded by a 3 mm gap. Each gap was filled with bone allograft or ProOsteon with or without OP-1 delivered in a bovine collagen type I carrier (OP-1 device). 300 microg OP-1 was used in the 0.75 cc gap surrounding the implant. After 3 weeks, the OP-1 device enhanced implant fixation by 800% (p

Originalsprog	Engelsk
Tidsskrift	Acta Orthopaedica
Vol/bind	73
Udgave nummer	1
Sider (fra-til)	31-9
Antal sider	9
ISSN	1745-3674
DOI	https://doi.org/10.1080/000164702317281378
Status	Udgivet - 2002
Udgivet eksternt	Ja

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abstract = "In each femoral condyle of 8 Labrador dogs, a non weight-bearing hydroxyapatite-coated implant was inserted surrounded by a 3 mm gap. Each gap was filled with bone allograft or ProOsteon with or without OP-1 delivered in a bovine collagen type I carrier (OP-1 device). 300 microg OP-1 was used in the 0.75 cc gap surrounding the implant. After 3 weeks, the OP-1 device enhanced implant fixation by 800\% (p",

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AU - Jensen, Thomas B

AU - Overgaard, Søren

AU - Lind, Martin

AU - Rahbek, Ole

AU - Bünger, Cody

AU - Søballe, Kjeld

PY - 2002

Y1 - 2002

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AB - In each femoral condyle of 8 Labrador dogs, a non weight-bearing hydroxyapatite-coated implant was inserted surrounded by a 3 mm gap. Each gap was filled with bone allograft or ProOsteon with or without OP-1 delivered in a bovine collagen type I carrier (OP-1 device). 300 microg OP-1 was used in the 0.75 cc gap surrounding the implant. After 3 weeks, the OP-1 device enhanced implant fixation by 800% (p

UR - https://www.scopus.com/pages/publications/0036121718

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DO - 10.1080/000164702317281378

M3 - Journal article

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JO - Acta Orthopaedica

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Osteogenic protein 1 device increases bone formation and bone graft resorption around cementless implants

Abstract

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