Optimal voxel size for measuring global gray and white matter proton metabolite concentrations using chemical shift imaging.

Lars Peter Grüner Hanson, E Adalsteinsson, A Pfefferbaum, D.M. Spielman

12 Citationer (Scopus)

Abstract

Quantification of gray and white matter levels of spectroscopically visible metabolites can provide important insights into brain development and pathological conditions. Chemical shift imaging offers a gain in efficiency for estimation of global gray and white matter metabolite concentrations compared to single voxel methods. In the present study, the optimal voxel size is calculated from segmented human brain data and accompanying field maps. The optimal voxel size is found to be approximately 8 cc, but a wide range of values, 4-64 cc, can be chosen with little increase in estimated concentration error (<15%). Magn Reson Med 44:10-18, 2000.
OriginalsprogEngelsk
TidsskriftMagnetic Resonance in Medicine
Vol/bind44
Udgave nummer1
Sider (fra-til)10-18
Antal sider8
ISSN0740-3194
StatusUdgivet - 2000

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