Opposite effects of pioglitazone and rosiglitazone on mitochondrial respiration in skeletal muscle of patients with type 2 diabetes

R Rabøl; R Boushel; T Almdal; C N Hansen; T Ploug; S B Haugaard; C Prats; S Madsbad; F Dela

doi:10.1111/j.1463-1326.2010.01237.x

Opposite effects of pioglitazone and rosiglitazone on mitochondrial respiration in skeletal muscle of patients with type 2 diabetes

R Rabøl, R Boushel, T Almdal, C N Hansen, T Ploug, S B Haugaard, C Prats, S Madsbad, F Dela

40 Citationer (Scopus)

Abstract

Udgivelsesdato: 2010-Sep

Originalsprog	Engelsk
Tidsskrift	Diabetic Medicine
Vol/bind	12
Udgave nummer	9
Sider (fra-til)	806-14
Antal sider	8
ISSN	0742-3071
DOI	https://doi.org/10.1111/j.1463-1326.2010.01237.x
Status	Udgivet - 2010

Adgang til dokumentet

10.1111/j.1463-1326.2010.01237.x

Citationsformater

@article{1861151f9aef4505a11ea5bb5fb9abc8,

title = "Opposite effects of pioglitazone and rosiglitazone on mitochondrial respiration in skeletal muscle of patients with type 2 diabetes",

abstract = "Skeletal muscle insulin resistance has been linked to mitochondrial dysfunction. We examined how improvements in muscular insulin sensitivity following rosiglitazone (ROSI) or pioglitazone (PIO) treatment would affect muscle mitochondrial function in patients with type 2 diabetes mellitus (T2DM).",

keywords = "Body Mass Index, Cell Respiration, Diabetes Mellitus, Type 2, Female, Hemoglobin A, Glycosylated, Humans, Hypoglycemic Agents, Immunohistochemistry, Insulin Resistance, Male, Middle Aged, Mitochondria, Muscle, Muscle, Skeletal, Thiazolidinediones",

author = "R Rab{\o}l and R Boushel and T Almdal and Hansen, {C N} and T Ploug and Haugaard, {S B} and C Prats and S Madsbad and F Dela",

year = "2010",

doi = "10.1111/j.1463-1326.2010.01237.x",

language = "English",

volume = "12",

pages = "806--14",

journal = "Diabetic Medicine",

issn = "0742-3071",

publisher = "Wiley",

number = "9",

}

TY - JOUR

T1 - Opposite effects of pioglitazone and rosiglitazone on mitochondrial respiration in skeletal muscle of patients with type 2 diabetes

AU - Rabøl, R

AU - Boushel, R

AU - Almdal, T

AU - Hansen, C N

AU - Ploug, T

AU - Haugaard, S B

AU - Prats, C

AU - Madsbad, S

AU - Dela, F

PY - 2010

Y1 - 2010

N2 - Skeletal muscle insulin resistance has been linked to mitochondrial dysfunction. We examined how improvements in muscular insulin sensitivity following rosiglitazone (ROSI) or pioglitazone (PIO) treatment would affect muscle mitochondrial function in patients with type 2 diabetes mellitus (T2DM).

AB - Skeletal muscle insulin resistance has been linked to mitochondrial dysfunction. We examined how improvements in muscular insulin sensitivity following rosiglitazone (ROSI) or pioglitazone (PIO) treatment would affect muscle mitochondrial function in patients with type 2 diabetes mellitus (T2DM).

KW - Body Mass Index

KW - Cell Respiration

KW - Diabetes Mellitus, Type 2

KW - Female

KW - Hemoglobin A, Glycosylated

KW - Humans

KW - Hypoglycemic Agents

KW - Immunohistochemistry

KW - Insulin Resistance

KW - Male

KW - Middle Aged

KW - Mitochondria, Muscle

KW - Muscle, Skeletal

KW - Thiazolidinediones

U2 - 10.1111/j.1463-1326.2010.01237.x

DO - 10.1111/j.1463-1326.2010.01237.x

M3 - Journal article

C2 - 20649633

SN - 0742-3071

VL - 12

SP - 806

EP - 814

JO - Diabetic Medicine

JF - Diabetic Medicine

IS - 9

ER -

Opposite effects of pioglitazone and rosiglitazone on mitochondrial respiration in skeletal muscle of patients with type 2 diabetes

Abstract

Adgang til dokumentet

Fingeraftryk

Citationsformater