Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

On the relation between dimensions of fatigue and depression in adolescents and young adults with acquired brain injury

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Harvard

APA

CBE

MLA

Vancouver

Author

Bibtex

@article{0afb0179d3504ee39203b4b328fc1db2,
title = "On the relation between dimensions of fatigue and depression in adolescents and young adults with acquired brain injury",
abstract = "Complaints of fatigue following acquired brain injury (ABI) are often associated with depression. However, the nature of this relationship is unclear; furthermore, research among young people with ABI is limited. The objective of this cross-sectional study was (1) to investigate levels of depression in young outpatients with ABI (15-30 years old) and (2) to determine how different dimensions of fatigue relate to depression. Five dimensions of fatigue were assessed with the Multidimensional Fatigue Inventory (MFI-20), and depression was assessed with the Major Depression Inventory (MDI). Mann-Whitney U-tests and multiple regression analyses were conducted. The ABI group ( n = 105), on average 23.7 years old ( SD = 4.2) and 31 months post-injury ( SD = 61), had elevated levels of fatigue and depression compared to a convenience sample of 160 healthy controls, all p's < .001. In multivariate analyses, the predominantly mental dimensions of fatigue, General Fatigue, Mental Fatigue, and Reduced Motivation, were independently associated with MDI, all p's < .01, while the physical dimensions, Physical Fatigue and Reduced Activity, were not. Distinctions within the concept of fatigue may be important in relation to depression, and future research could benefit from adopting a multidimensional approach in the development of more targeted and effective treatments of fatigue and depression following ABI.",
keywords = "acquired brain injury, depression, Fatigue, Multidimensional Fatigue Inventory, young adults",
author = "{Dornonville de la Cour}, {Frederik L} and Forchhammer, {Birgitte H} and Jesper Mogensen and Anne Norup",
year = "2020",
month = "6",
doi = "10.1080/09602011.2018.1517368",
language = "English",
volume = "30",
pages = "872--887",
journal = "Neuropsychological Rehabilitation",
issn = "0960-2011",
publisher = "Psychology Press",
number = "5",

}

RIS

TY - JOUR

T1 - On the relation between dimensions of fatigue and depression in adolescents and young adults with acquired brain injury

AU - Dornonville de la Cour, Frederik L

AU - Forchhammer, Birgitte H

AU - Mogensen, Jesper

AU - Norup, Anne

PY - 2020/6

Y1 - 2020/6

N2 - Complaints of fatigue following acquired brain injury (ABI) are often associated with depression. However, the nature of this relationship is unclear; furthermore, research among young people with ABI is limited. The objective of this cross-sectional study was (1) to investigate levels of depression in young outpatients with ABI (15-30 years old) and (2) to determine how different dimensions of fatigue relate to depression. Five dimensions of fatigue were assessed with the Multidimensional Fatigue Inventory (MFI-20), and depression was assessed with the Major Depression Inventory (MDI). Mann-Whitney U-tests and multiple regression analyses were conducted. The ABI group ( n = 105), on average 23.7 years old ( SD = 4.2) and 31 months post-injury ( SD = 61), had elevated levels of fatigue and depression compared to a convenience sample of 160 healthy controls, all p's < .001. In multivariate analyses, the predominantly mental dimensions of fatigue, General Fatigue, Mental Fatigue, and Reduced Motivation, were independently associated with MDI, all p's < .01, while the physical dimensions, Physical Fatigue and Reduced Activity, were not. Distinctions within the concept of fatigue may be important in relation to depression, and future research could benefit from adopting a multidimensional approach in the development of more targeted and effective treatments of fatigue and depression following ABI.

AB - Complaints of fatigue following acquired brain injury (ABI) are often associated with depression. However, the nature of this relationship is unclear; furthermore, research among young people with ABI is limited. The objective of this cross-sectional study was (1) to investigate levels of depression in young outpatients with ABI (15-30 years old) and (2) to determine how different dimensions of fatigue relate to depression. Five dimensions of fatigue were assessed with the Multidimensional Fatigue Inventory (MFI-20), and depression was assessed with the Major Depression Inventory (MDI). Mann-Whitney U-tests and multiple regression analyses were conducted. The ABI group ( n = 105), on average 23.7 years old ( SD = 4.2) and 31 months post-injury ( SD = 61), had elevated levels of fatigue and depression compared to a convenience sample of 160 healthy controls, all p's < .001. In multivariate analyses, the predominantly mental dimensions of fatigue, General Fatigue, Mental Fatigue, and Reduced Motivation, were independently associated with MDI, all p's < .01, while the physical dimensions, Physical Fatigue and Reduced Activity, were not. Distinctions within the concept of fatigue may be important in relation to depression, and future research could benefit from adopting a multidimensional approach in the development of more targeted and effective treatments of fatigue and depression following ABI.

KW - acquired brain injury

KW - depression

KW - Fatigue

KW - Multidimensional Fatigue Inventory

KW - young adults

U2 - 10.1080/09602011.2018.1517368

DO - 10.1080/09602011.2018.1517368

M3 - Journal article

VL - 30

SP - 872

EP - 887

JO - Neuropsychological Rehabilitation

JF - Neuropsychological Rehabilitation

SN - 0960-2011

IS - 5

ER -

ID: 56482438