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Region Hovedstaden - en del af Københavns Universitetshospital
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Omalizumab for chronic urticaria: a case series and overview of the literature

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Omalizumab is a recombinant humanized monoclonal antibody that blocks the high-affinity Fc receptor of IgE. Omalizumab has been approved for the treatment of moderate to severe asthma; however, there is currently more and more data showing promising results in the management also of chronic urticaria. We present a case series of 19 patients with chronic urticaria treated in a university department with omalizumab and give an overview of the existing literature comprising an additional 59 cases as well as a total of 139 patients enrolled in two randomized controlled trials comparing omalizumab with placebo. The collective evidence points to omalizumab as a safe and effective treatment option for patients with chronic urticaria who do not sufficiently respond to standard therapy as recommended by existing guidelines.
OriginalsprogEngelsk
TidsskriftCase Reports in Dermatology
Vol/bind4
Udgave nummer1
Sider (fra-til)19-26
Antal sider8
ISSN1662-6567
DOI
StatusUdgivet - 2012

ID: 36872786