Olorofim Susceptibility Testing of 1,423 Danish Mold Isolates Obtained in 2018-2019 Confirms Uniform and Broad-Spectrum Activity

Keyphrases

• Susceptibility Testing 100%
• Olorofim 100%
• Broad-spectrum Activity 100%
• Fumigatus 66%
• Modal 33%
• European Committee on Antimicrobial Susceptibility Testing (EUCAST) 33%
• Species Complex 33%
• PyrE 33%
• Aspergillus Fumigatus 16%
• Single Center 16%
• Phase II Trial 16%
• In Vitro Activity 16%
• Target Enzyme 16%
• Terreus 16%
• Aspergillus Species 16%
• Antifungal Drugs 16%
• Population Data 16%
• Dermatophytes 16%
• Trichophyton Rubrum 16%
• Azole-resistant 16%
• Epidemiological Cut-off Values 16%
• MIC50 16%
• Flavus 16%
• Novel Antifungals 16%
• Mucorales 16%
• MIC90 16%
• Dihydroorotate Dehydrogenase (DHODH) 16%
• Scedosporium 16%

Immunology and Microbiology

• Minimum Inhibitory Concentration 100%
• Mould 100%
• Dilution 20%
• Wild Type 20%
• Aspergillus fumigatus 10%
• Aspergillus 10%
• Dermatophyte 10%
• Trichophyton Rubrum 10%
• MIC50 10%
• Mucorales 10%
• MIC90 10%
• Scedosporium 10%