Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

OCT based interpretation of the optic nerve head anatomy in young adults with retinal vascular occlusions and ischemic optic neuropathy

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Non-invasive measurement techniques for quantitative assessment of optic nerve head blood flow

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  2. Anterior lamina cribrosa surface position in idiopathic intracranial hypertension and glaucoma

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Intracranial pressure and optic disc changes in a rat model of obstructive hydrocephalus

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Detection of oedema on optical coherence tomography images using deep learning model trained on noisy clinical data

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. An update on the clinical approach to giant cell arteritis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

PURPOSE: To examine optic nerve head (ONH) anatomy in young adults with central retinal vein occlusion (CRVO), branch retinal vein occlusion (BRVO), central retinal artery occlusion (CRAO), branch retinal artery occlusion (BRAO) or nonarteritic anterior ischemic optic neuropathy (NA-AION) in order to look for associated, potentially predisposing anomalies.

METHODS: Cross-sectional study including 54 patients (ages 16-50 years) diagnosed from 2009 to 2018 with CRVO, BRVO, CRAO, BRAO, or NA-AION. Using Optical Coherence Tomography the presence of optic disc drusen (ODD), prelaminar hyperreflective lines and peripapillary hyperreflective ovoid mass-like structures (PHOMS), and determination of scleral canal size, retinal nerve fiber layer thickness (RNFLT) and macular ganglion cell layer thickness (GCLT) was obtained. Data for retinal vascular occlusion patients were grouped and analyzed together.

RESULTS: ODD were found in 13% of all patients, 2% of retinal vascular occlusion patients and 67% of NA-AION patients (p < 0.0001). Prelaminar hyperreflective lines were found in 35% of all patients, 24% of retinal vascular occlusion patients and 89% of NA-AION patients (p = 0.0005). PHOMS were found in 20% of all patients, 13% of retinal vascular occlusion patients and 56% of NA-AION patients (p = 0.012). RNFLT was decreased in ODD patients compared to patients without ODD (p = 0.01). Scleral canal diameter and GCLT was not correlated with ODD, prelaminar hyperreflective lines or PHOMS.

CONCLUSION: ODD, prelaminar hyperreflective lines and PHOMS were more frequent in NA-AION patients compared to retinal vascular occlusion patients. The prevalence of ODD in retinal vascular occlusion patients was similar to the reported prevalence in the general population.

OriginalsprogEngelsk
TidsskriftEuropean Journal of Ophthalmology
Vol/bind31
Udgave nummer5
Sider (fra-til)2563-2570
Antal sider8
ISSN1120-6721
DOI
StatusUdgivet - sep. 2021

ID: 61986413