Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Obstetrical complications in dichorionic twin pregnancies in women with polycystic ovary syndrome

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. The impact of cardiovascular diseases on maternal deaths in the Nordic countries

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Breech and induction. Time for evidence-based informed consent

    Publikation: Bidrag til tidsskriftLetterForskningpeer review

  3. Maternal pre-pregnancy overweight and infertility in sons and daughters: a cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Adhesive bowel obstruction: Incidence, recurrence and 30-day mortality in Danish women 1984-2013 - A national cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Prevalence and treatment of group B streptococcus colonization based on risk factors versus intrapartum culture screening

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Danish doctors' reactions to 'internationalization' in clinical training in a public university hospital

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

INTRODUCTION: Both women with polycystic ovary syndrome (PCOS) and women with twin pregnancies have increased risk of adverse pregnancy outcome. The aim of this study was to investigate the impact of PCOS and maternal androgen levels on the outcome of dichorionic twin pregnancy.

MATERIAL AND METHODS: A retrospective study of 360 women with dichorionic twin pregnancies: 72 PCOS women from a fertility clinic (years 1997 to 2010) and 288 non-PCOS women from a hospital cohort (years 2005 to 2007). The obstetrical outcome was extracted from Danish National registers and supplemented by patient file data. 65% of the PCOS group had a registered pre-pregnancy androgen level and these were stratified into normo- and hyperandrogenic women. The groups were compared by multiple regression analysis adjusting for mode of conception and pre-pregnancy body mass index.

RESULTS: We found no overall impact of PCOS on the pregnancy outcome; the risk of preeclampsia, gestational diabetes and preterm delivery were comparable within the groups. However, five deliveries in the PCOS group compared to two in the control group occurred before gestational week 28. No difference in the obstetrical outcome between hyperandrogenic and normoandrogenic women was found. The body mass index in the PCOS population was lower than in the non-PCOS, possibly reflecting a higher socioeconomic status and a healthier lifestyle, which may underestimate the impact of a PCOS diagnosis.

CONCLUSION: Neither PCOS nor maternal androgen levels confer additional risks to the outcome of dichorionic twin pregnancies of normal weight women. This article is protected by copyright. All rights reserved.

OriginalsprogEngelsk
TidsskriftActa Obstetricia et Gynecologica Scandinavica
Vol/bind96
Udgave nummer12
Sider (fra-til)1453-1459
ISSN0001-6349
DOI
StatusUdgivet - 1 dec. 2017

ID: 51820282