Observations on regional cerebral blood flow in cortical and subcortical structures during language production in normal man

C W Wallesch; L Henriksen; H H Kornhuber; O B Paulson

doi:10.1016/0093-934x(85)90082-3

Observations on regional cerebral blood flow in cortical and subcortical structures during language production in normal man

C W Wallesch, L Henriksen, H H Kornhuber, O B Paulson

Abstract

Regional cerebral blood flow (rCBF) was studied by single photon emission computerized tomography (SPECT) of inhaled xenon-133 in six normal volunteers during various language, articulatory, and control conditions. Language production increased rCBF in predominantly left-sided cortical and subcortical areas. The involved regions were anatomically related to a left frontal area (Broca's), to both caudate nuclei, to a left thalamic/pallidal area, and bilaterally in retrorolandic areas. The failure to demonstrate lateralized retrorolandic activity is thought to reflect the complexity of the tasks.

Originalsprog	Engelsk
Tidsskrift	Brain and Language
Vol/bind	25
Udgave nummer	2
Sider (fra-til)	224-33
Antal sider	10
ISSN	0093-934X
DOI	https://doi.org/10.1016/0093-934x(85)90082-3
Status	Udgivet - jul. 1985
Udgivet eksternt	Ja

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10.1016/0093-934x(85)90082-3

Citationsformater

@article{9e372d6c913540648b0bbe26adbe2567,

title = "Observations on regional cerebral blood flow in cortical and subcortical structures during language production in normal man",

abstract = "Regional cerebral blood flow (rCBF) was studied by single photon emission computerized tomography (SPECT) of inhaled xenon-133 in six normal volunteers during various language, articulatory, and control conditions. Language production increased rCBF in predominantly left-sided cortical and subcortical areas. The involved regions were anatomically related to a left frontal area (Broca's), to both caudate nuclei, to a left thalamic/pallidal area, and bilaterally in retrorolandic areas. The failure to demonstrate lateralized retrorolandic activity is thought to reflect the complexity of the tasks.",

keywords = "Adult, Caudate Nucleus/blood supply, Cerebrovascular Circulation, Female, Frontal Lobe/blood supply, Functional Laterality/physiology, Humans, Language, Male, Memory/physiology, Speech/physiology, Temporal Lobe/blood supply, Thalamus/blood supply, Tomography, Emission-Computed, Xenon Radioisotopes",

author = "Wallesch, {C W} and L Henriksen and Kornhuber, {H H} and Paulson, {O B}",

year = "1985",

month = jul,

doi = "10.1016/0093-934x(85)90082-3",

language = "English",

volume = "25",

pages = "224--33",

journal = "Brain and Language",

issn = "0093-934X",

publisher = "Academic Press",

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}

TY - JOUR

T1 - Observations on regional cerebral blood flow in cortical and subcortical structures during language production in normal man

AU - Wallesch, C W

AU - Henriksen, L

AU - Kornhuber, H H

AU - Paulson, O B

PY - 1985/7

Y1 - 1985/7

N2 - Regional cerebral blood flow (rCBF) was studied by single photon emission computerized tomography (SPECT) of inhaled xenon-133 in six normal volunteers during various language, articulatory, and control conditions. Language production increased rCBF in predominantly left-sided cortical and subcortical areas. The involved regions were anatomically related to a left frontal area (Broca's), to both caudate nuclei, to a left thalamic/pallidal area, and bilaterally in retrorolandic areas. The failure to demonstrate lateralized retrorolandic activity is thought to reflect the complexity of the tasks.

AB - Regional cerebral blood flow (rCBF) was studied by single photon emission computerized tomography (SPECT) of inhaled xenon-133 in six normal volunteers during various language, articulatory, and control conditions. Language production increased rCBF in predominantly left-sided cortical and subcortical areas. The involved regions were anatomically related to a left frontal area (Broca's), to both caudate nuclei, to a left thalamic/pallidal area, and bilaterally in retrorolandic areas. The failure to demonstrate lateralized retrorolandic activity is thought to reflect the complexity of the tasks.

KW - Adult

KW - Caudate Nucleus/blood supply

KW - Cerebrovascular Circulation

KW - Female

KW - Frontal Lobe/blood supply

KW - Functional Laterality/physiology

KW - Humans

KW - Language

KW - Male

KW - Memory/physiology

KW - Speech/physiology

KW - Temporal Lobe/blood supply

KW - Thalamus/blood supply

KW - Tomography, Emission-Computed

KW - Xenon Radioisotopes

U2 - 10.1016/0093-934x(85)90082-3

DO - 10.1016/0093-934x(85)90082-3

M3 - Journal article

C2 - 3877544

SN - 0093-934X

VL - 25

SP - 224

EP - 233

JO - Brain and Language

JF - Brain and Language

IS - 2

ER -

Observations on regional cerebral blood flow in cortical and subcortical structures during language production in normal man

Abstract

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