Ny test til diagnostik af tuberkulose

Pernille Ravn, Michala Vaaben Rose, Bolette Søborg, Ase Bengård Andersen

2 Citationer (Scopus)


The performance of two commercially-available Interferon Gamma Release Assays, QuantiFERON-TB-Gold and T-SPOT-TB, is reviewed. The tests can indirectly detect M. tuberculosis infection based on T-cell recognition of specific proteins which are not present in the BCG vaccine M. avium, or most other environmental mycobacteria.The sensitivity (76-88%) of the IGRAs is not optimal for a diagnostic test for active tuberculosis. However, the specificity is high (92-97%), and the IGRAs may play an important role in the investigation for active tuberculosis and screening for latent tuberculosis infection in BCG vaccinated populations and immunosuppressed patients.
Udgivelsesdato: 2009-Sep-7
Bidragets oversatte titelNew diagnostic test for tuberculosis
TidsskriftUgeskr Laeger
Udgave nummer37
Sider (fra-til)2635-9
Antal sider4
StatusUdgivet - 2009