Nonselective matrix metalloproteinase but not tumor necrosis factor-α inhibition effectively preserves the early critical colon anastomotic integrity

Sven Per Magnus Ågren, Thomas L Andersen, Line Andersen, Christine Bruun Schiødt, Vikas Surve, Troels T. Andreassen, Juha Risteli, Lennart E Franzén, Jean-Marie Delaissé, Anne-Marie Heegaard, Lars Nannestad Jørgensen

24 Citationer (Scopus)

Abstract

Increased matrix metalloproteinase (MMP) activity has been implicated in the pathogenesis of colorectal anastomotic leakage. Tumor necrosis factor-α (TNF-α) induces MMPs and may influence anastomosis repair.
OriginalsprogEngelsk
TidsskriftInternational Journal of Colorectal Disease
Vol/bind26
Udgave nummer3
Sider (fra-til)329-37
Antal sider9
ISSN0179-1958
DOI
StatusUdgivet - 1 mar. 2011

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