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Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

No increased sperm DNA fragmentation index in semen containing human papillomavirus or herpesvirus

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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  • Maja Døvling Kaspersen
  • Mona Berger Håkonsen Bungum
  • Jens Fedder
  • J Bonde
  • P B Larsen
  • H J Ingerslev
  • Per Höllsberg
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It remains unknown whether human papillomaviruses (HPVs) or human herpesviruses (HHVs) in semen affect sperm DNA integrity. We investigated whether the presence of these viruses in semen was associated with an elevated sperm DNA fragmentation index. Semen from 76 sperm donors was examined by a PCR-based hybridization array that identifies all HHVs and 35 of the most common HPVs. Sperm DNA integrity was determined by the sperm chromatin structure assay. HPVs or HHVs, or both, were found in 57% of semen samples; however, sperm DNA fragmentation index was not increased in semen containing these viruses.
OriginalsprogEngelsk
TidsskriftAndrology
Vol/bind1
Udgave nummer3
Sider (fra-til)361-4
Antal sider4
ISSN2047-2927
DOI
StatusUdgivet - maj 2013

ID: 42845904