Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

No effect of fibrin sealant on drain output or functional recovery following simultaneous bilateral total knee arthroplasty

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. The problem is not necessarily the data, it is the interpretation

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Days alive and out of hospital after fast-track total hip and knee arthroplasty: an observational cohort study in 16 137 patients

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. A national center for persistent severe pain after groin hernia repair: Five-year prospective data

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer
Background and purpose Blood loss after total knee arthroplasty (TKA) may lead to anemia, blood transfusions, and increased total costs. Also, bleeding into the periarticular tissue may cause swelling and a reduction in quadriceps strength, thus impairing early functional recovery. In this randomized, double-blind, placebo-controlled study, we analyzed the possible effect of fibrin sealant on blood loss and early functional recovery in a fast-track setting. Methods 24 consecutive patients undergoing bilateral simultaneous TKA were included. 10 mL of fibrin sealant (Evicel) was sprayed onto one knee whereas the contralateral knee had saline. Drain output, the primary outcome, was measured from knee drains removed exactly 24 h after surgery. Secondary outcomes (knee swelling, pain, strength of knee extension, and range of movement (ROM)) were evaluated up to 21 days after surgery. Results The drain output in knees treated with fibrin sealant and placebo was similar (582 mL and 576 mL, respectively). Likewise, no statistically significant differences were found between groups regarding swelling, pain, strength of knee extension, and ROM. Interpretation Fibrin sealant as a local hemostatic in TKA showed no benefit in reducing drain output or in facilitating early functional recovery when used with a tourniquet, tranexamic acid, and a femoral bone plug.
OriginalsprogEngelsk
TidsskriftActa Orthopaedica (Print Edition)
Vol/bind84
Udgave nummer2
Sider (fra-til)153-158
ISSN1745-3674
DOI
StatusUdgivet - 2013

ID: 36758163