New strict left bundle branch block criteria reflect left ventricular activation differences

Kasper Janus Grønn Emerek; Niels Risum; Søren Hjortshøj; Sam Riahi; Jeppe Grøndahl Rasmussen; Poul Erik Bloch Thomsen; Claus Graff; Peter Søgaard

doi:10.1016/j.jelectrocard.2015.07.008

New strict left bundle branch block criteria reflect left ventricular activation differences

Kasper Janus Grønn Emerek, Niels Risum, Søren Hjortshøj, Sam Riahi, Jeppe Grøndahl Rasmussen, Poul Erik Bloch Thomsen, Claus Graff, Peter Søgaard

7 Citationer (Scopus)

Abstract

AIMS: Pacing lead electrical delays and strict left bundle branch block (LBBB) criteria were assessed against cardiac resynchronization therapy (CRT) outcome.

METHODS: Forty-nine patients with LBBB and QRS duration >130 milliseconds underwent CRT-implantation. Sensed right ventricular to left ventricular electrical delay (RV-LV-IED) was measured. Response to CRT was defined as ≥15% decrease in left ventricular end-systolic volume.

RESULTS: Eighteen of 20 (90%) patients with non-ischemic dilated cardiomyopathy (DCM) and 18 of 29 (62%) with ischemic heart disease (IHD) responded to CRT, p<0.01. When applying new strict ECG criteria subsequent rates of response in DCM were 18/19 (95%) and in IHD of 18/23 (78%) respectively, p<0.05 between IHD groups. Correspondingly, RV-LV-IED was longer in DCM compared to IHD patients and in responders compared to non-responders, p=0.017 and p<0.001, respectively.

CONCLUSION: Interventricular electrical delay predicts left ventricular remodeling after CRT and new, strict ECG criteria of LBBB are superior in predicting remodeling.

Originalsprog	Engelsk
Tidsskrift	Journal of Electrocardiology
Vol/bind	48
Udgave nummer	5
Sider (fra-til)	758-62
Antal sider	5
ISSN	0022-0736
DOI	https://doi.org/10.1016/j.jelectrocard.2015.07.008
Status	Udgivet - 4 aug. 2015

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10.1016/j.jelectrocard.2015.07.008

Citationsformater

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title = "New strict left bundle branch block criteria reflect left ventricular activation differences",

abstract = "AIMS: Pacing lead electrical delays and strict left bundle branch block (LBBB) criteria were assessed against cardiac resynchronization therapy (CRT) outcome.METHODS: Forty-nine patients with LBBB and QRS duration >130 milliseconds underwent CRT-implantation. Sensed right ventricular to left ventricular electrical delay (RV-LV-IED) was measured. Response to CRT was defined as ≥15% decrease in left ventricular end-systolic volume.RESULTS: Eighteen of 20 (90%) patients with non-ischemic dilated cardiomyopathy (DCM) and 18 of 29 (62%) with ischemic heart disease (IHD) responded to CRT, p<0.01. When applying new strict ECG criteria subsequent rates of response in DCM were 18/19 (95%) and in IHD of 18/23 (78%) respectively, p<0.05 between IHD groups. Correspondingly, RV-LV-IED was longer in DCM compared to IHD patients and in responders compared to non-responders, p=0.017 and p<0.001, respectively.CONCLUSION: Interventricular electrical delay predicts left ventricular remodeling after CRT and new, strict ECG criteria of LBBB are superior in predicting remodeling.",

author = "Emerek, {Kasper Janus Gr{\o}nn} and Niels Risum and S{\o}ren Hjortsh{\o}j and Sam Riahi and Rasmussen, {Jeppe Gr{\o}ndahl} and {Bloch Thomsen}, {Poul Erik} and Claus Graff and Peter S{\o}gaard",

year = "2015",

month = aug,

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doi = "10.1016/j.jelectrocard.2015.07.008",

language = "English",

volume = "48",

pages = "758--62",

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TY - JOUR

T1 - New strict left bundle branch block criteria reflect left ventricular activation differences

AU - Emerek, Kasper Janus Grønn

AU - Risum, Niels

AU - Hjortshøj, Søren

AU - Riahi, Sam

AU - Rasmussen, Jeppe Grøndahl

AU - Bloch Thomsen, Poul Erik

AU - Graff, Claus

AU - Søgaard, Peter

PY - 2015/8/4

Y1 - 2015/8/4

N2 - AIMS: Pacing lead electrical delays and strict left bundle branch block (LBBB) criteria were assessed against cardiac resynchronization therapy (CRT) outcome.METHODS: Forty-nine patients with LBBB and QRS duration >130 milliseconds underwent CRT-implantation. Sensed right ventricular to left ventricular electrical delay (RV-LV-IED) was measured. Response to CRT was defined as ≥15% decrease in left ventricular end-systolic volume.RESULTS: Eighteen of 20 (90%) patients with non-ischemic dilated cardiomyopathy (DCM) and 18 of 29 (62%) with ischemic heart disease (IHD) responded to CRT, p<0.01. When applying new strict ECG criteria subsequent rates of response in DCM were 18/19 (95%) and in IHD of 18/23 (78%) respectively, p<0.05 between IHD groups. Correspondingly, RV-LV-IED was longer in DCM compared to IHD patients and in responders compared to non-responders, p=0.017 and p<0.001, respectively.CONCLUSION: Interventricular electrical delay predicts left ventricular remodeling after CRT and new, strict ECG criteria of LBBB are superior in predicting remodeling.

AB - AIMS: Pacing lead electrical delays and strict left bundle branch block (LBBB) criteria were assessed against cardiac resynchronization therapy (CRT) outcome.METHODS: Forty-nine patients with LBBB and QRS duration >130 milliseconds underwent CRT-implantation. Sensed right ventricular to left ventricular electrical delay (RV-LV-IED) was measured. Response to CRT was defined as ≥15% decrease in left ventricular end-systolic volume.RESULTS: Eighteen of 20 (90%) patients with non-ischemic dilated cardiomyopathy (DCM) and 18 of 29 (62%) with ischemic heart disease (IHD) responded to CRT, p<0.01. When applying new strict ECG criteria subsequent rates of response in DCM were 18/19 (95%) and in IHD of 18/23 (78%) respectively, p<0.05 between IHD groups. Correspondingly, RV-LV-IED was longer in DCM compared to IHD patients and in responders compared to non-responders, p=0.017 and p<0.001, respectively.CONCLUSION: Interventricular electrical delay predicts left ventricular remodeling after CRT and new, strict ECG criteria of LBBB are superior in predicting remodeling.

U2 - 10.1016/j.jelectrocard.2015.07.008

DO - 10.1016/j.jelectrocard.2015.07.008

M3 - Journal article

C2 - 26233647

SN - 0022-0736

VL - 48

SP - 758

EP - 762

JO - Journal of Electrocardiology

JF - Journal of Electrocardiology

IS - 5

ER -

New strict left bundle branch block criteria reflect left ventricular activation differences

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