@article{a878810e398b468eb46b512aa350f3a7,
title = "New peptide receptor radionuclide therapy of invasive cancer cells: in vivo studies using 177Lu-DOTA-AE105 targeting uPAR in human colorectal cancer xenografts",
abstract = "The proposition of uPAR as a potential target in cancer therapy is advanced by its predominant expression at the invasive front of colorectal cancer (CRC) and its value as prognostic biomarker for poor survival in this disease. In this study, we provide the first in vivo proof-of-concept for a theranostic approach as treatment modality in a human xenograft colorectal cancer model.",
keywords = "Animals, Beta Particles, Cell Transformation, Neoplastic, Colorectal Neoplasms, Dideoxynucleosides, Female, HT29 Cells, Heterocyclic Compounds, 1-Ring, Humans, Lutetium, Mice, Molecular Targeted Therapy, Neoplasm Invasiveness, Oligopeptides, Positron-Emission Tomography, Radioisotopes, Receptors, Urokinase Plasminogen Activator, Substrate Specificity",
author = "Morten Persson and Rasmussen, {Palle Damkj{\ae}r} and Jacob Madsen and Michael Ploug and Andreas Kjaer",
note = "Copyright {\textcopyright} 2012 Elsevier Inc. All rights reserved.",
year = "2012",
doi = "10.1016/j.nucmedbio.2012.05.007",
language = "English",
volume = "39",
pages = "962--9",
journal = "Nuclear Medicine and Biology",
issn = "0969-8051",
publisher = "Elsevier Inc",
number = "7",
}