TY - JOUR
T1 - Neurophysiological and psychosocial mechanisms of fibromyalgia
T2 - A comprehensive review and call for an integrative model
AU - Pinto, Ana Margarida
AU - Luís, Mariana
AU - Geenen, Rinie
AU - Palavra, Filipe
AU - Lumley, Mark A
AU - Ablin, Jacob N
AU - Amris, Kirstine
AU - Branco, Jaime
AU - Buskila, Dan
AU - Castelhano, João
AU - Castelo-Branco, Miguel
AU - Crofford, Leslie J
AU - Fitzcharles, Mary-Ann
AU - Häuser, Winfried
AU - Kosek, Eva
AU - Mease, Philip J
AU - Marques, Tiago Reis
AU - Jacobs, Johannes W G
AU - Castilho, Paula
AU - da Silva, José A P
N1 - Copyright © 2023 Elsevier Ltd. All rights reserved.
PY - 2023/8
Y1 - 2023/8
N2 - Research into the neurobiological and psychosocial mechanisms involved in fibromyalgia has progressed remarkably in recent years. Despite this, current accounts of fibromyalgia fail to capture the complex, dynamic, and mutual crosstalk between neurophysiological and psychosocial domains. We conducted a comprehensive review of the existing literature in order to: a) synthesize current knowledge on fibromyalgia; b) explore and highlight multi-level links and pathways between different systems; and c) build bridges connecting disparate perspectives. An extensive panel of international experts in neurophysiological and psychosocial aspects of fibromyalgia discussed the collected evidence and progressively refined and conceptualized its interpretation. This work constitutes an essential step towards the development of a model capable of integrating the main factors implicated in fibromyalgia into a single, unified construct which appears indispensable to foster the understanding, assessment, and intervention for fibromyalgia.
AB - Research into the neurobiological and psychosocial mechanisms involved in fibromyalgia has progressed remarkably in recent years. Despite this, current accounts of fibromyalgia fail to capture the complex, dynamic, and mutual crosstalk between neurophysiological and psychosocial domains. We conducted a comprehensive review of the existing literature in order to: a) synthesize current knowledge on fibromyalgia; b) explore and highlight multi-level links and pathways between different systems; and c) build bridges connecting disparate perspectives. An extensive panel of international experts in neurophysiological and psychosocial aspects of fibromyalgia discussed the collected evidence and progressively refined and conceptualized its interpretation. This work constitutes an essential step towards the development of a model capable of integrating the main factors implicated in fibromyalgia into a single, unified construct which appears indispensable to foster the understanding, assessment, and intervention for fibromyalgia.
KW - Humans
KW - Fibromyalgia
KW - Models, Biopsychosocial
UR - http://www.scopus.com/inward/record.url?scp=85160577223&partnerID=8YFLogxK
U2 - 10.1016/j.neubiorev.2023.105235
DO - 10.1016/j.neubiorev.2023.105235
M3 - Review
C2 - 37207842
SN - 0149-7634
VL - 151
SP - 105235
JO - Neuroscience and Biobehavioral Reviews
JF - Neuroscience and Biobehavioral Reviews
M1 - 105235
ER -