Neuropeptides and neural cell adhesion molecule (NCAM) in CSF from patients with ALS

L Werdelin, A Gjerris, G Boysen, J Fahrenkrug, O S Jørgensen, J F Rehfeld

12 Citationer (Scopus)

Abstract

In 10 patients with amyotrophic lateral sclerosis (ALS), the CSF content of the neuropeptides vasoactive intestinal polypeptide (VIP) and cholecystokinin (CCK) as well as neural cell adhesion molecule (NCAM) was investigated. Compared with normal controls, no deviations were found in CCK or NCAM, while the values of VIP were significantly lower in ALS patients. This finding may reflect a loss of motor neurons.

OriginalsprogEngelsk
TidsskriftActa Neurologica Scandinavica
Vol/bind79
Udgave nummer3
Sider (fra-til)177-81
Antal sider5
ISSN0001-6314
DOI
StatusUdgivet - mar. 1989
Udgivet eksterntJa

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