Neonatal bronchial hyperresponsiveness precedes acute severe viral bronchiolitis in infants

Bo L K Chawes; Porntiva Poorisrisak; Sebastian L Johnston; Hans Bisgaard

doi:10.1016/j.jaci.2012.04.045

Neonatal bronchial hyperresponsiveness precedes acute severe viral bronchiolitis in infants

Bo L K Chawes, Porntiva Poorisrisak, Sebastian L Johnston, Hans Bisgaard

Afdeling for Allergi, Hud- og Kønssygdomme HGH

65 Citationer (Scopus)

Abstract

Respiratory syncytial virus and other respiratory tract viruses lead to common colds in most infants, whereas a minority develop acute severe bronchiolitis often requiring hospitalization. We hypothesized that such an excessive response to respiratory tract viral infection is caused by host factors reflected in pre-existing increased bronchial responsiveness.

Originalsprog	Engelsk
Tidsskrift	Journal of Allergy and Clinical Immunology
Vol/bind	130
Udgave nummer	2
Sider (fra-til)	354-61.e3
Antal sider	8
ISSN	0091-6749
DOI	https://doi.org/10.1016/j.jaci.2012.04.045
Status	Udgivet - 2012

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title = "Neonatal bronchial hyperresponsiveness precedes acute severe viral bronchiolitis in infants",

abstract = "Respiratory syncytial virus and other respiratory tract viruses lead to common colds in most infants, whereas a minority develop acute severe bronchiolitis often requiring hospitalization. We hypothesized that such an excessive response to respiratory tract viral infection is caused by host factors reflected in pre-existing increased bronchial responsiveness.",

keywords = "Acute Disease, Bronchial Hyperreactivity, Bronchial Provocation Tests, Bronchiolitis, Viral, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Methacholine Chloride, Prospective Studies, Respiratory Function Tests, Respiratory Syncytial Virus Infections, Respiratory Syncytial Viruses, Severity of Illness Index, Time Factors",

author = "Chawes, \{Bo L K\} and Porntiva Poorisrisak and Johnston, \{Sebastian L\} and Hans Bisgaard",

year = "2012",

doi = "10.1016/j.jaci.2012.04.045",

language = "English",

volume = "130",

pages = "354--61.e3",

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TY - JOUR

T1 - Neonatal bronchial hyperresponsiveness precedes acute severe viral bronchiolitis in infants

AU - Chawes, Bo L K

AU - Poorisrisak, Porntiva

AU - Johnston, Sebastian L

AU - Bisgaard, Hans

PY - 2012

Y1 - 2012

N2 - Respiratory syncytial virus and other respiratory tract viruses lead to common colds in most infants, whereas a minority develop acute severe bronchiolitis often requiring hospitalization. We hypothesized that such an excessive response to respiratory tract viral infection is caused by host factors reflected in pre-existing increased bronchial responsiveness.

AB - Respiratory syncytial virus and other respiratory tract viruses lead to common colds in most infants, whereas a minority develop acute severe bronchiolitis often requiring hospitalization. We hypothesized that such an excessive response to respiratory tract viral infection is caused by host factors reflected in pre-existing increased bronchial responsiveness.

KW - Acute Disease

KW - Bronchial Hyperreactivity

KW - Bronchial Provocation Tests

KW - Bronchiolitis, Viral

KW - Child, Preschool

KW - Female

KW - Humans

KW - Infant

KW - Infant, Newborn

KW - Male

KW - Methacholine Chloride

KW - Prospective Studies

KW - Respiratory Function Tests

KW - Respiratory Syncytial Virus Infections

KW - Respiratory Syncytial Viruses

KW - Severity of Illness Index

KW - Time Factors

UR - https://www.scopus.com/pages/publications/84864476809

U2 - 10.1016/j.jaci.2012.04.045

DO - 10.1016/j.jaci.2012.04.045

M3 - Journal article

C2 - 22713595

SN - 0091-6749

VL - 130

SP - 354-61.e3

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

IS - 2

ER -

Neonatal bronchial hyperresponsiveness precedes acute severe viral bronchiolitis in infants

Abstract

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