TY - JOUR
T1 - Neonatal bloodstream infections in a pediatric hospital in Vietnam
T2 - a cohort study
AU - Kruse, Alexandra Yasmin
AU - Thieu Chuong, Do Huu
AU - Phuong, Cam Ngoc
AU - Duc, Than
AU - Graff Stensballe, Lone
AU - Prag, Jorgen
AU - Kurtzhals, Jorgen
AU - Greisen, Gorm
AU - Pedersen, Freddy Karup
PY - 2013/12
Y1 - 2013/12
N2 - Septicemia and bloodstream infections (BSIs) are major causes of neonatal morbidity and mortality in developing countries. We prospectively recorded all positive blood cultures (BSI) among neonates admitted consecutively to a tertiary pediatric hospital in Vietnam during a 12-month period. Among 5763 neonates, 2202 blood cultures were performed, of which 399 were positive in 385 neonates. Among these, 64 died, 62 in relation to septicemia. Of the BSI isolates, 56% was known pathogenic and 48% was gram-negative bacteria, most frequently Klebsiella spp. (n = 78), Acinetobacter spp. (n = 58) and Escherichia coli (n = 21). Only three Streptococcus spp. were identified, none group B. Resistance against antibiotics applied was common. The mortality was highest in neonates with gram-negative BSI compared with no confirmed BSI and gram-positive BSI (P
AB - Septicemia and bloodstream infections (BSIs) are major causes of neonatal morbidity and mortality in developing countries. We prospectively recorded all positive blood cultures (BSI) among neonates admitted consecutively to a tertiary pediatric hospital in Vietnam during a 12-month period. Among 5763 neonates, 2202 blood cultures were performed, of which 399 were positive in 385 neonates. Among these, 64 died, 62 in relation to septicemia. Of the BSI isolates, 56% was known pathogenic and 48% was gram-negative bacteria, most frequently Klebsiella spp. (n = 78), Acinetobacter spp. (n = 58) and Escherichia coli (n = 21). Only three Streptococcus spp. were identified, none group B. Resistance against antibiotics applied was common. The mortality was highest in neonates with gram-negative BSI compared with no confirmed BSI and gram-positive BSI (P
U2 - 10.1093/tropej/fmt056
DO - 10.1093/tropej/fmt056
M3 - Journal article
C2 - 23868576
SN - 0142-6338
VL - 59
SP - 483
EP - 488
JO - Journal of Tropical Pediatrics
JF - Journal of Tropical Pediatrics
IS - 6
ER -