Neoantigen reactive T cells correlate with the low mutational burden in hematological malignancies

Sunil Kumar Saini; Staffan Holmberg-Thydén; Anne-Mette Bjerregaard; Ashwin Unnikrishnan; Simon Dorfmüller; Uwe Platzbecker; Irene Tirado-Gonzalez; Halvard Bönig; Daniel El Fassi; Kirsten Grønbæk; John Pimanda; Hind Medyouf; Sine Reker Hadrup

doi:10.1038/s41375-022-01705-y

Neoantigen reactive T cells correlate with the low mutational burden in hematological malignancies

Sunil Kumar Saini, Staffan Holmberg-Thydén, Anne-Mette Bjerregaard, Ashwin Unnikrishnan, Simon Dorfmüller, Uwe Platzbecker, Irene Tirado-Gonzalez, Halvard Bönig, Daniel El Fassi, Kirsten Grønbæk, John Pimanda, Hind Medyouf, Sine Reker Hadrup^*

^*Corresponding author af dette arbejde

Afdeling for Blodsygdomme

Originalsprog	Engelsk
Tidsskrift	Leukemia
Vol/bind	36
Udgave nummer	11
Sider (fra-til)	2734-2738
Antal sider	5
ISSN	0887-6924
DOI	https://doi.org/10.1038/s41375-022-01705-y
Status	Udgivet - nov. 2022

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10.1038/s41375-022-01705-y

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Citationsformater

Saini, S. K., Holmberg-Thydén, S., Bjerregaard, A-M., Unnikrishnan, A., Dorfmüller, S., Platzbecker, U., Tirado-Gonzalez, I., Bönig, H., El Fassi, D., Grønbæk, K., Pimanda, J., Medyouf, H., & Hadrup, S. R. (2022). Neoantigen reactive T cells correlate with the low mutational burden in hematological malignancies. Leukemia, 36(11), 2734-2738. https://doi.org/10.1038/s41375-022-01705-y

Saini, SK, Holmberg-Thydén, S, Bjerregaard, A-M, Unnikrishnan, A, Dorfmüller, S, Platzbecker, U, Tirado-Gonzalez, I, Bönig, H, El Fassi, D , Grønbæk, K, Pimanda, J, Medyouf, H & Hadrup, SR 2022, 'Neoantigen reactive T cells correlate with the low mutational burden in hematological malignancies', Leukemia, bind 36, nr. 11, s. 2734-2738. https://doi.org/10.1038/s41375-022-01705-y

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title = "Neoantigen reactive T cells correlate with the low mutational burden in hematological malignancies",

keywords = "Antigens, Neoplasm, CD8-Positive T-Lymphocytes, Hematologic Neoplasms/genetics, Humans, Immunotherapy, Mutation",

author = "Saini, {Sunil Kumar} and Staffan Holmberg-Thyd{\'e}n and Anne-Mette Bjerregaard and Ashwin Unnikrishnan and Simon Dorfm{\"u}ller and Uwe Platzbecker and Irene Tirado-Gonzalez and Halvard B{\"o}nig and {El Fassi}, Daniel and Kirsten Gr{\o}nb{\ae}k and John Pimanda and Hind Medyouf and Hadrup, {Sine Reker}",

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doi = "10.1038/s41375-022-01705-y",

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T1 - Neoantigen reactive T cells correlate with the low mutational burden in hematological malignancies

AU - Saini, Sunil Kumar

AU - Holmberg-Thydén, Staffan

AU - Bjerregaard, Anne-Mette

AU - Unnikrishnan, Ashwin

AU - Dorfmüller, Simon

AU - Platzbecker, Uwe

AU - Tirado-Gonzalez, Irene

AU - Bönig, Halvard

AU - El Fassi, Daniel

AU - Grønbæk, Kirsten

AU - Pimanda, John

AU - Medyouf, Hind

AU - Hadrup, Sine Reker

PY - 2022/11

Y1 - 2022/11

KW - Antigens, Neoplasm

KW - CD8-Positive T-Lymphocytes

KW - Hematologic Neoplasms/genetics

KW - Humans

KW - Immunotherapy

KW - Mutation

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U2 - 10.1038/s41375-022-01705-y

DO - 10.1038/s41375-022-01705-y

M3 - Letter

C2 - 36209321

VL - 36

SP - 2734

EP - 2738

JO - Leukemia

JF - Leukemia

SN - 0887-6924

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