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Necrotizing Soft-Tissue Infections: Clinical Features and Diagnostic Aspects

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@article{46b5fadab1e04854a03d8ea6e189ba75,
title = "Necrotizing Soft-Tissue Infections: Clinical Features and Diagnostic Aspects",
abstract = "The term necrotizing soft-tissue infection (NSTI) encompasses a heterogenous group of patients with necrotizing infections, involving any body part. NSTI is diagnosed by surgical exploration, where necrosis of the subcutaneous tissue and/or muscle tissue, undermining of the skin, thrombosis of the superficial veins, and deliquescent tissue can be seen. Patients can present with vague symptoms, and approximately half of patients experience severe pain. The clinical presentation and microbiological etiology vary according to affected body site, with NSTI located to the extremities being dominated by monomicrobial group A streptococcal infections, and NSTI located to the anogenital area dominated by polymicrobial infections. No set of diagnostic criteria exists, and suspicion of the diagnosis should come from careful clinical examination and signs of local or systemic severity. Laboratory blood values show no distinct pattern but resemble those of sepsis. Imaging can aid the diagnostic process but must not delay surgical intervention.",
keywords = "Clinical presentation, Diagnostic aspects, Fournier{\textquoteright}s gangrene, Microbiology, Necrotizing fasciitis, Necrotizing soft-tissue infections",
author = "Madsen, {Martin Bruun} and Per Arnell and Ole Hyldegaard",
year = "2020",
month = jan,
day = "1",
doi = "10.1007/978-3-030-57616-5_4",
language = "English",
volume = "1294",
pages = "39--52",
journal = "Advances in Experimental Medicine and Biology",
issn = "0065-2598",
publisher = "Springer New York LLC",

}

RIS

TY - JOUR

T1 - Necrotizing Soft-Tissue Infections

T2 - Clinical Features and Diagnostic Aspects

AU - Madsen, Martin Bruun

AU - Arnell, Per

AU - Hyldegaard, Ole

PY - 2020/1/1

Y1 - 2020/1/1

N2 - The term necrotizing soft-tissue infection (NSTI) encompasses a heterogenous group of patients with necrotizing infections, involving any body part. NSTI is diagnosed by surgical exploration, where necrosis of the subcutaneous tissue and/or muscle tissue, undermining of the skin, thrombosis of the superficial veins, and deliquescent tissue can be seen. Patients can present with vague symptoms, and approximately half of patients experience severe pain. The clinical presentation and microbiological etiology vary according to affected body site, with NSTI located to the extremities being dominated by monomicrobial group A streptococcal infections, and NSTI located to the anogenital area dominated by polymicrobial infections. No set of diagnostic criteria exists, and suspicion of the diagnosis should come from careful clinical examination and signs of local or systemic severity. Laboratory blood values show no distinct pattern but resemble those of sepsis. Imaging can aid the diagnostic process but must not delay surgical intervention.

AB - The term necrotizing soft-tissue infection (NSTI) encompasses a heterogenous group of patients with necrotizing infections, involving any body part. NSTI is diagnosed by surgical exploration, where necrosis of the subcutaneous tissue and/or muscle tissue, undermining of the skin, thrombosis of the superficial veins, and deliquescent tissue can be seen. Patients can present with vague symptoms, and approximately half of patients experience severe pain. The clinical presentation and microbiological etiology vary according to affected body site, with NSTI located to the extremities being dominated by monomicrobial group A streptococcal infections, and NSTI located to the anogenital area dominated by polymicrobial infections. No set of diagnostic criteria exists, and suspicion of the diagnosis should come from careful clinical examination and signs of local or systemic severity. Laboratory blood values show no distinct pattern but resemble those of sepsis. Imaging can aid the diagnostic process but must not delay surgical intervention.

KW - Clinical presentation

KW - Diagnostic aspects

KW - Fournier’s gangrene

KW - Microbiology

KW - Necrotizing fasciitis

KW - Necrotizing soft-tissue infections

U2 - 10.1007/978-3-030-57616-5_4

DO - 10.1007/978-3-030-57616-5_4

M3 - Journal article

C2 - 33079362

VL - 1294

SP - 39

EP - 52

JO - Advances in Experimental Medicine and Biology

JF - Advances in Experimental Medicine and Biology

SN - 0065-2598

ER -

ID: 61082483