Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes

P V Højberg, Pär-Ola Mikael Zander, Tina Vilsbøll, F K Knop, T Krarup, Anders Vølund, Jens Møller Holst, S Madsbad

83 Citationer (Scopus)

Abstract

The ability of glucagon-like peptide-1 (GLP-1) to enhance beta cell responsiveness to i.v. glucose is impaired in patients with type 2 diabetes mellitus compared with healthy individuals. We investigated whether 4 weeks of near normalisation of blood glucose (BG) improves the potentiation of glucose-stimulated insulin secretion by GLP-1.
OriginalsprogEngelsk
TidsskriftDiabetologia
Vol/bind51
Udgave nummer4
Sider (fra-til)632-40
Antal sider9
ISSN0012-186X
DOI
StatusUdgivet - 1 apr. 2008

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