@article{f4a48303b6434c0fa670e6daeff8e2dd,
title = "Natural CD4+ T-cell responses against indoleamine 2,3-dioxygenase",
abstract = "The enzyme indoleamine 2,3-dioxygenase (IDO) contributes to immune tolerance in a variety of settings. In cancer IDO is expressed within the tumor itself as well as in antigen-presenting cells in tumor-draining lymph nodes, where it endorses the establishment of peripheral immune tolerance to tumor antigens. Recently, we described cytotoxic CD8(+) T-cell reactivity towards IDO-derived peptides.",
keywords = "Aged, Antineoplastic Agents, CD8-Positive T-Lymphocytes, Epitopes, Female, HLA-A2 Antigen, Histocompatibility Antigens Class II, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, Interferon-gamma, Interleukin-10, Interleukin-17, Male, Melanoma, Middle Aged, Peptides, T-Lymphocytes, Helper-Inducer, Tumor Necrosis Factor-alpha",
author = "Shamaila Munir and Larsen, {Stine Kiaer} and Iversen, {Trine Zeeberg} and Marco Donia and Klausen, {Tobias Wirenfeldt} and Svane, {Inge Marie} and {thor Straten}, Per and Andersen, {Mads Hald}",
year = "2012",
doi = "10.1371/journal.pone.0034568",
language = "English",
volume = "7",
pages = "e34568",
journal = "P L o S One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "4",
}