Naproxen prevention of heterotopic ossification after hip arthroplasty. A prospective control study of 55 patients.

Bidragets oversatte titel: Naproxen prevention of heterotopic ossification after hip arthroplasty. A prospective control study of 55 patients.

Peter Henrik Gebuhr, M Soelberg, T Orsnes, H Wilbek

48 Citationer (Scopus)

Abstract

The effect of naproxen on heterotopic ossification after total hip replacement was studied in a randomized, double-blind trial. Twenty-eight patients received 250 mg naproxen thrice daily for 4 weeks postoperatively starting on the morning of the operation while 27 control patients received a placebo. Three months after the operation, 13 patients in the control group had heterotopic ossification compared with 4 patients in the group that received naproxen; and after 1 year, the figures were 15 and 4, respectively (P less than 0.01). Three control patients had severe ossifications. We conclude that naproxen given for 4 weeks is sufficient to decrease the incidence of heterotopic ossification after cemented total hip replacement.
Bidragets oversatte titelNaproxen prevention of heterotopic ossification after hip arthroplasty. A prospective control study of 55 patients.
OriginalsprogEngelsk
TidsskriftActa Orthopaedica
Vol/bind62
Udgave nummer3
Sider (fra-til)226-229
Antal sider4
ISSN1745-3674
StatusUdgivet - 1991

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